Results 121 to 130 of about 5,660,601 (310)
Measurable sets of measures [PDF]
Dubins, Lester, Freedman, David
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The mean path length(MPL)of photons is a critical parameter to calculate tissue absorption coefficient as well as blood oxygenation using modified Beer-Lambert law,where in the differential path factor(DPF)is often assumed as constant over range of ...
SHANG Yu +4 more
doaj
Investigation of effects from realistic influences on inductive gap measurement
The influence of deviations from ideal square butt joint conditions is investigated for an improved inductive gap measurement method. Varying plate thickness, chamfers, and scratches are tested on Alloy 718 at different frequencies in a working range ...
Svenman, Edvard, +1 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A Study on Length Traceability and Diffraction Efficiency of Chromium Gratings
Measurement traceability is a prerequisite for achieving accurate and reliable results as well as technical standardization. The period of Chromium (Cr) gratings fabricated by atomic lithography can be directly traced back to natural constants.
Lihua Lei +8 more
doaj +1 more source
Since the 1960s, Nb-Ti, exhibiting a superconducting transition temperature Tc of 9K, and Nb3Sn, with a Tc of 18K have been the materials of choice for superconducting applications.
Bruneel, ElsWE068010009432800000-0002-6527-004XF4C6AE2E-F0ED-11E1-A9DE-61C894A0A6B4 +9 more
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source

