Results 31 to 40 of about 350,520 (261)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Preparation and Properties of Core-Shell Structure/Ni60 Coating

open access: yesShock and Vibration, 2021
As the most important element in improving the service life of a mechanical system, surface coating materials are of key importance in the development of high-end equipment.
Wang Xinsheng   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Filter for Millimeter Waves with Narrow Bandwidth

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2016
Mathematical model and model sample of the bandpass with central frequency of 140 GHz were presented. Comparison of theoretical and experimental data in the range of 75,…260 GHz was made.
A. P. Krenitskiy   +3 more
doaj  

Soft sensor modeling method for Pichia pastoris fermentation process based on substructure domain transfer learning

open access: yesBMC Biotechnology
Background Aiming at the problem that traditional transfer methods are prone to lose data information in the overall domain-level transfer, and it is difficult to achieve the perfect match between source and target domains, thus reducing the accuracy of ...
Bo Wang   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Volúmetro com câmaras comunicantes: apresentação de um protótipo de dimensões reduzidas desenvolvido para a avaliação objetiva do volume de mão Volumeter with communicating chambers: presentation of a prototype with reduced dimensions developed for objective assessment of hand volume

open access: yesJornal Vascular Brasileiro, 2010
A volumetria tradicional por deslocamento de água, que utiliza o princípio do transbordamento de Arquimedes, é considerada o padrão-ouro da avaliação do volume de membros, porém tem seu uso rotineiro prescindido por apresentar uma série de desvantagens ...
Rogério Mendonça de Carvalho   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Solar Radiation Measurement Tools and Their Impact on In Situ Testing—A Portuguese Case Study

open access: yesBuildings
Accurate knowledge of solar radiation data or its estimation is crucial to maximize the benefits derived from the Sun. In this context, many sectors are re-evaluating their investments and plans to increase profit margins in line with sustainable ...
Marta Oliveira   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy