Results 141 to 150 of about 50,666 (264)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Bidimensional structure and measurement equivalence of the Patient Health Questionnaire-9: sex-sensitive assessment of depressive symptoms in three representative German cohort studies. [PDF]

BMC Psychiatry, 2021
Tibubos AN, Otten D, Zöller D, Binder H, Wild PS, Fleischer T, Johar H, Atasoy S, Schulze L, Ladwig KH, Schomerus G, Linkohr B, Grabe HJ, Kruse J, Schmidt CO, Münzel T, König J, Brähler E, Beutel ME.   +18 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

On Measures Equivalent to Wiener Measure

The Annals of Mathematical Statistics, 1967
openaire   +3 more sources

Extending the CASO-N24 to Late Adolescence: Psychometric Properties and Measurement Equivalence in a Peruvian School Sample. [PDF]

Healthcare (Basel)
Aguilar-Armas HM, Vera-Calmet VG, Arbulú Ballesteros MA, Yglesias-Alva LA, Noé Grijalva HM, Quispe Villarreal MDC.   +5 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Assessment of Measurement Equivalence of the Communities That Care Brief Depression Scale by Immigrant Generation Status in Latinx Youth. [PDF]

J Community Psychol
Delawalla MLM, Rhew IC, Martinez G, Skinner M, Oesterle S, Guttmannova K.   +5 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Measurement equivalence of the UDS version 2.0 and 3.0 neuropsychological batteries. [PDF]

Alzheimers Dement
Gaynor LS, Lopez FV, Van Hulle CA, Li C, Vasunilashorn SM, Andrews SJ, Simone SM, Mungas DM.   +7 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source