Results 121 to 130 of about 2,708,723 (307)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Assessing parenting in racially and ethnically diverse families: A lack of measurement equivalence. [PDF]

J Fam Psychol, 2023
Rodriguez VJ, Cadet GJ, Sisitsky M, Cooley C, Acosta J, Coles E, Charity-Parker B, Walters A, Shaffer A, Parent J.   +9 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Are clinician-administered ataxia scales truly culture-free? Rethinking contextual validity in diverse populations

Frontiers in Neurology
Hereditary cerebellar ataxias are genetically and phenotypically heterogeneous progressive neurodegenerative disorders characterized by substantial functional impairment. With the emergence of disease-modifying therapies and gene-targeted clinical trials,
Hina Narzari, Ravi Yadav, Achal Kumar Srivastava, Pramod Kumar Pal, Divyani Garg   +4 more
doaj   +1 more source

Supplemental Material - Rethinking Measurement Equivalence in Comparative Political Research

Supplemental Material for Rethinking Measurement Equivalence in Comparative Political Research by Kirill Zhirkov and Christian Welzel in Comparative ...
Christian Welzel (778973), Kirill Zhirkov (16727911)   +1 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Measurement equivalence of family acceptance/rejection among sexual and gender minority youth by disclosure status. [PDF]

J Fam Psychol, 2023
Pollitt AM, Fish JN, Watson RJ.
europepmc   +1 more source

Equivalence Scales Declining with Expenditure: Evidence and Implications for Income Distribution [PDF]

We estimate expenditure dependent equivalence scales for Italian couples with and without children. Following Donaldson and Pendakur (2006) we incorporate the generalized absolute equivalence-scale exactness (GAESE) restrictions into a translated ...
Fabrizio Balli, Silvia Tiezzi
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Psychometric Properties of Different Short Forms of Social Interaction Anxiety Scale in Chinese College Students

Psychology Research and Behavior Management
Qian Song,1,2,* Kaili Zheng,1,2,* Zixia Ding,1,2 Zhengmiao Miao,1,2 Zhaoxia Liu,1,2 Ming Cheng,3 Jinyao Yi1,2,4 1Medical Psychological Center, the Second Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 2Medical ...
Song Q, Zheng K, Ding Z, Miao Z, Liu Z, Cheng M, Yi J   +6 more
doaj