Results 111 to 120 of about 2,708,723 (307)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Measurement equivalence of the dispositional resistance to change scale

, 2011
Measurement equivalence of the dispositional resistance to change ...
M Vakola (13737721), J Han (7409606), R Barkauskiene (13737730), N Bozionelos (13514329), N Jimmieson (9895571), H Mitsuhashi (13737739), M Bayazit (13737718), B Mlacic (13737742), K van Dam (13335450), I Feric (13737745), J Kordacova (13737736), Y Fujimoto (9896129), H Hetland (13737757), S Ohly (13737751), M Hrebickova (13737733), L Gonzalez (9298217), S Oreg (13737715), A Armenakis (13737727), M Kotrla (13737748), I Saksvik (13737760), L Arciniega (13737724), P Saksvik (13737754)   +21 more
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Equivalent measures of dependence

Journal of Multivariate Analysis, 1983
AbstractThe maximal correlation between a pair of σ-fields A and B becomes arbitrarily small as sup{|P(A ⋔ B) − P(A) P(B)|/[P(A) P(B)]1/2, A ∈ A, B ∈ B, P(A) > 0, P(B) > 0} becomes sufficiently small.
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Equivalence of low-cost PM10 concentration measuring devices with a reference method using various correction functions

Economics and Environment
The aim of the study was to build a corrective model that can be used in the analysed devices and to assess the impact of such a model on the values of the measured concentrations. The novelty of this study is the test of equivalence with the equivalent
Tomasz Owczarek, Mariusz Rogulski, Piotr O. Czechowski, Artur Badyda, Ernest Czermański   +4 more
doaj   +1 more source

Diagnosing Measurement Equivalence in Cross-National Research

Many researchers have pointed out that it is necessary to ensure measurement equivalence in cross-national comparative research. Three aspects of measurement equivalence, translation, metric, and calibration equivalence, are necessary to establish the ...
Michael R Mullen
core  

Cross-cultural measurement equivalence of generalized trust. Evidence from the European Social Survey (2002 and 2004)

, 2008
Generalized trust, Measurement, Cross-cultural equivalence, European Social Survey, Social capital,
Tim Reeskens, Marc Hooghe, Hooghe, Marc, Reeskens, Tim   +3 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Establishing Data Collection Procedures Equivalence in International Business Research [PDF]

Following a number of earlier studies on data equivalence in cross-cultural international business research, this article uses a content analysis of articles published in four leading international business journals from 2000 to 2009, to uncover the ...
Agnieszka Chidlow, Pervez N. Ghauri
core