Results 101 to 110 of about 48,611 (263)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Assessing the measurement invariance of Free Will and Determinism Plus scale across four languages: a registered report

Royal Society Open Science
Free will is assumed to be the core of an individual’s self-concept. Belief in free will has been studied extensively and was found to be correlated with many behavioural and psychological outcomes.
Siqi Duan, Chenghao Zhou, Qinglan Liu, Yixin Gong, Zenan Dou, Jingguang Li, Hu Chuan-Peng   +6 more
doaj   +1 more source

Measurement equivalence of the paper-based and electronic version of the Integrated Palliative care Outcome Scale (IPOS): A randomised crossover trial. [PDF]

Palliat Med, 2023
Bolzani A, Kupf S, Hodiamont F, Burner-Fritsch I, Bausewein C, Ramsenthaler C.   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Are we measuring loneliness in the same way in men and women in the general population and in the older population? Two studies of measurement equivalence. [PDF]

PLoS One, 2022
Pollet TV, Thompson A, Malcolm C, McCarty K, Saxton TK, Roberts SGB.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Measurement Equivalence between the Original and Estimated Mini-Mental State Examination in People with Dementia. [PDF]

Int J Environ Res Public Health, 2021
Chiu EC, Chien TH, Lee YC.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Testing the cross-cultural measurement invariance of the Penn state worry questionnaire for children (PSWQ-C) across Poland and the United States of America

Scientific Reports
The Penn State Worry Questionnaire for Children (PSWQ-C), developed by Bruce F. Chorpita, is a tool used worldwide for evaluating worry in children. The original US English PSWQ-C has been translated into several other languages and there is support for ...
Elżbieta B. Talik, Manuel S. Sprung, Bruce F. Chorpita   +2 more
doaj   +1 more source

Estimating measurement equivalence of the 12-item General Health Questionnaire across ethnic groups in the UK. [PDF]

Psychol Med, 2023
King K, Allum N, Stoneman P, Cernat A.
europepmc   +1 more source