Results 81 to 90 of about 2,708,723 (307)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Artificial Examples of Empirical Equivalence [PDF]
, 2013 In this paper I analyze three artificial examples of empirical equivalence: van Fraassen’s alternative formulations of Newton’s theory, the Poincaré-Reichenbach argument for the conventionality of geometry; and predictively equivalent ‘systems of the ...
Acuña, Pablo
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Methoden, Daten, Analysen, 2018 One of the central and constantly recurring features of youth participation studies is the depiction of young people and adolescents as the future of democratic politics.
Christian Schnaudt, Michael Weinhardt
doaj +1 more source
Some curiosites about the Engel method to estimate equivalence scales [PDF]
This paper lends legitimacy to the food share as an indicator of welfare by demonstrating the conditions necessary in empirical work for the Engel method of estimating equivalence scales to provide an exact measure of welfare.
Federico Perali
core
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Measuring Poverty in South Africa [PDF]
, 1999 This paper sets out the methodological issues for the measurement of poverty before presenting a poverty profile of South Africa. It tests the sensitivity of the poverty profile to choices around the metric used to measure well-being, the equivalence ...
Leibbrandt, Murray, Woolard, Ingrid
core +1 more source
, 2013 MEASUREMENT EQUIVALENCE OF THE SOUTH AFRICAN PSYCHOLOGICAL OWNERSHIP QUESTIONNAIRE FOR DIVERSE SOUTH AFRICAN CULTURAL GROUPS Measurement equivalence of the south african psychological ownership questionnaire for diverse south african cultural groups (-
Schaap, Pieter, Olckers, Chantal
core +1 more source
Measurement Instruments for the Social Sciences, 2019 Declining response rates worldwide have stimulated interest in understanding what may be influencing this decline and how it varies across countries and survey populations.
Edith de Leeuw +4 more
doaj +1 more source