Results 61 to 70 of about 51,269 (265)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Impact of Partial Measurement Invariance on Testing Moderation for Single and Multi-Level Data

Frontiers in Psychology, 2018
Moderation effect is a commonly used concept in the field of social and behavioral science. Several studies regarding the implication of moderation effects have been done; however, little is known about how partial measurement invariance influences the ...
Yu-Yu Hsiao, Mark H. C. Lai
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Reference material comparisons: design of experiment and processing of measurement results

Стандартные образцы, 2017
The present article describes general principles of experimental research and processing of measurement results within the framework of one of the methods of evaluating the interchangeability of reference materials - paired comparisons of reference ...
E. V. Osintseva
doaj  

Psychometric Properties of the Chinese Version of the Neuroticism Subscale of the NEO-PI

Frontiers in Psychology, 2018
Neuroticism is an important concept in psychology, self-report measures of neuroticism are important for both research and clinical practice. The neuroticism subscale of the Neuroticism-Extraversion-Openness Personality Inventory (NEO-PI) is a brief ...
Chang Xi, Mingtian Zhong, Xiaoxia Lei, Ying Liu, Yu Ling, Xiongzhao Zhu, Xiongzhao Zhu, Shuqiao Yao, Shuqiao Yao, Jinyao Yi, Jinyao Yi   +10 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Measurement Equivalence of Diabetes Self-Management, Distress, and Quality-of-Life Measures in Adults with Type 2 Diabetes in Vietnam

Nursing Reports
Background: Patient-reported outcome comparisons require measurement equivalence, which is seldom tested in low- and middle-income country (LMIC) diabetes research. We examined equivalence of the Diabetes Self-Management Instrument-35 (DSMI-35), Diabetes
Thu-Thuy Thi Nguyen, Huu Thuan Vo, Thi Tuong Vi Nguyen, Pham Minh Son, Vu Thi Xim, Thi My Nhung Pham, Mieu An Phan, Thi Anh Nguyen   +7 more
doaj   +1 more source