Results 51 to 60 of about 2,708,723 (307)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Measurement Equivalence Testing 2.0
, 2018 Probably the most ignored assumption in the social and behavioral sciences is the assumption that measures are observed without error. Ignoring measurement error when it is present will result in conclusions that are biased to some degree. A second commonly ignored assumption is that survey measures can be used to make valid comparisons between (groups
Veld, W.M. van der, Saris, W.E.
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Free products, orbit equivalence and measure equivalence rigidity
Groups, Geometry, and Dynamics, 2012 We study the analogue, in orbit equivalence, of free product decompositions and free indecomposability for countable groups. We introduce the (orbit equivalence invariant) notion of freely indecomposable ( \mathcal{FI} ) standard probability measure preserving equivalence relations and ...
Alvarez, Aurélien, Gaboriau, Damien
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Is the Bland-Altman plot method useful without inferences for accuracy, precision, and agreement? [PDF]
Revista de Saúde PúblicaOBJECTIVE This study aims to propose a comprehensive alternative to the Bland-Altman plot method, addressing its limitations and providing a statistical framework for evaluating the equivalences of measurement techniques.
Paulo Sergio Panse Silveira +2 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Equivalence–Singularity Dichotomy in Markov Measures
Journal of Theoretical Probability, 2022 We establish an equivalence-singularity dichotomy for a large class of one-dimensional Markov measures. Our approach is new in that we deal with one-sided and two-sided chains simultaneously, and in that we do not appeal to any 0-1 law. In fact we deduce a new 0-1 law from the dichotomy.
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A Conceptual Method of Maintaining Equivalence in International Market Research
Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu, 2020 This paper focuses on equivalence in international market research and the conditions for maintaining such an equivalence. Equivalence was defined, in the field of research on an international scale, as an attribute of the results of research conducted ...
Magdalena Jaciow
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
An Equivalent Condition for the Existence of a Measurable Cardinal [PDF]
Proceedings of the American Mathematical Society, 1969 Introduction. The main purpose of this paper is to prove the equivalence of the existence of a topological space in which there is a nonconvergent open ultrafilter with the countable intersection property and the existence of a measurable cardinal. This paper will answer indirectly the open question in [2 ]. 1.1 DEFINITION.
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