Results 101 to 110 of about 1,100,257 (311)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Permissible Maximum Errors of Measurement Instruments in Metering Systems of Fluids [PDF]
Journal of Electrical and Electronics Engineering, 2014 The control and calibration of measuring instruments installed in dynamic metering station must have a good understanding of the evaluation and validation method of the error.
HARROUZ Abdelkader +2 more
doaj
Covariate Balancing With Measurement Error
Statistics in MedicineABSTRACT In recent years, there is a growing body of causal inference literature focusing on covariate balancing methods. These methods eliminate observed confounding by equalizing covariate moments between the treated and control groups.
Xialing Wen, Ying Yan
openaire +3 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Kinematics Error Compensation for a Surface Measurement Probe on an Ultra-Precision Turning Machine
Micromachines, 2018 In order to enhance the measurement availability for manufacturing applications, on-machine surface measurement (OMSM) is integrated onto the machine tools, which avoids the errors caused by re-positioning workpieces and utilizes the machine axes to ...
Duo Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Measurement error and statistical disclosure control [PDF]
, 2010 Statistical agencies release microdata to researchers after applying statistical disclosure control (SDC) methods. Noise addition is a perturbative SDC method which is carried out by adding independent random noise to a continuous variable or by ...
Shlomo, Natalie, Natalie Shlomo
core +1 more source
Accounting for Measurement Error and Untruthfulness in Binary RRT Models
MathematicsThis study examines the effect of measurement error on binary Randomized Response Technique models. We discuss a method for estimating and accounting for measurement error and untruthfulness in two basic models and one comprehensive model.
Bailey Meche +3 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source