Results 101 to 110 of about 4,820,822 (305)

Evaluasi Kinerja Alat Ukur Tinggi Muka Air Otomatis Menggunakan Kalibrator Di Laboratorium

open access: yesJurnal Teknik Hidraulik, 2019
Water resources infrastructure development requires a careful planning, one of which requires hydrological analysis. The accuracy of hydrological data is influenced by the method, operator/observer, and the performance of the measuring instrument.
Isnan Fauzan Akrom, Hany Agustiani
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Permissible Maximum Errors of Measurement Instruments in Metering Systems of Fluids [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2014
The control and calibration of measuring instruments installed in dynamic metering station must have a good understanding of the evaluation and validation method of the error.
HARROUZ Abdelkader   +2 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Measurement error in time-series analysis: a simulation study comparing modelled and monitored data. [PDF]

open access: yes, 2013
BACKGROUND: Assessing health effects from background exposure to air pollution is often hampered by the sparseness of pollution monitoring networks. However, regional atmospheric chemistry-transport models (CTMs) can provide pollution data with national ...
Richard W Atkinson   +25 more
core   +3 more sources

Correction of Scanning Steps to Improve Accuracy in Interferometric Profilometer

open access: yesMeasurement Science Review, 2015
In scanning interferometry of longitudinal shift, an uncertainty of required phase shift performance leads to a measurement error. Such uncertainty can be caused by external factors (vibrations, air turbulence in measuring area etc.) as well as ...
Sysoev E.   +3 more
doaj   +1 more source

Covariate Balancing With Measurement Error

open access: yesStatistics in Medicine
ABSTRACT In recent years, there is a growing body of causal inference literature focusing on covariate balancing methods. These methods eliminate observed confounding by equalizing covariate moments between the treated and control groups.
Xialing Wen, Ying Yan
openaire   +3 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Comparing the efficiency of structural and functional methods in measurement error models [PDF]

open access: yes, 2006
The paper is a survey of recent investigations by the authors and others into the relative efficiencies of structural and functional estimators of the regression parameters in a measurement error model.
Kukush, Alexander, Schneeweiß, Hans
core   +1 more source

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