Results 131 to 140 of about 1,100,257 (311)
Assessing the Efficiency of an Insurance Provider - A Measurement Error Approach [PDF]
The purpose of this paper is to compare the cost efficiency of private and public property insurance providers in Switzerland. The most commonly used measure for this kind of exercise is the Claims / Premium ratio.
Mario JAMETTI +1 more
core +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Correction for covariate measurement error in nonparametric regression [PDF]
, 2006 Many areas of applied statistics have become aware of the problem of measurement error-prone variables and their appropriate analysis. Simply ignoring the error in the analysis usually leads to biased estimates, like e.g.
Rummel, David
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
On heteroscedastic covariate measurement error in Cox regression
, 2017 Many survival studies have error-contaminated covariates, which may lack a gold standard of measurement. Furthermore, the error distribution can depend on the true covariates but the dependence structure is typically difficult to quantify ...
Huang, Yijian
core
, 2007 Objective. To assess the degree and source of measurement error in functional balance and mobility tests for people with stroke, and to identify the most effective method of data collection to minimize error.Design.
Tyson, S, Sarah F. Tyson
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
A renaissance for measurement error [PDF]
International Journal of Epidemiology, 2001 openaire +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Control Charts and the Effect of the Two-Component Measurement Error Model
Monitoring algorithms, such as the Shewhart and Cusum control charts, are often used for monitoring purposes in the chemical industry or within an environmental context.
Michele Scagliarini, Daniela Cocchi
core