Results 141 to 150 of about 4,820,822 (305)
Research of Tooth Profile Error Evaluation Method based on Cartesian Coordinate Measurement Method
Jixie chuandong, 2016 The tooth profile error is one important individual errors of gear,with wide use of the coordinate measuring machine in gear measurement,the Cartesian coordinate measuring method is becoming more and more widely applied in gear error measurement field ...
Zhang Bai, Lin Jiachun
doaj
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Measurement Error In Cross-Sectional and Longitudinal Labor Market Surveys: Results From Two Validation Studies [PDF]
This paper reports evidence on the error properties of survey reports of labor market variables such as earnings and work hours. Our primary data source is the PSID Validation Study, a two-wave panel survey of a sample of workers employed by a large firm
Willard L Rodgers +3 more
core
Regression Calibration in Measurement Error Modeling
, 2017 When a p-dimensional parameter θ is defined through the moment condition Em(X,θ) = 0, a simple estimation procedure of θ is proposed by Hong and Tamer when X, a k-dimensional random vector, is contaminated with Laplace measurement error U, that is, we can
Song, Weixing
core +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Covariate Measurement Error:Bias Reduction under Response-based Sampling [PDF]
In this paper we propose a general framework to deal with the presence of covariate measurement error (CME) in response-based (RB) samples. Using Chesher’s (1991) methodology, we obtain a small error variance approximation for the contaminated sampling ...
Esmeralda Ramalho
core
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source