Results 181 to 190 of about 544,111 (317)

A new instrument for the compliance control of cast resin insulated windings

open access: yes, 2015
In this paper, a new instrument for the compliance control in the production process of windings is proposed. It has been specifically designed for windings of MV-LV cast resin transformers, by implementing a SFRA (Sweep Frequency Response Analysis ...
FIORUCCI, EDOARDO   +4 more
core  

Assessment of Pregnant Women's Knowledge, Attitudes, and Habits Regarding Oral Health: Development and Validation of a Measurement Instrument. [PDF]

open access: yesInt J Environ Res Public Health
Kresina HG   +7 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Advanced measurement systems based on digital processing techniques for superconducting LHC magnets

open access: yes, 2006
The Large Hadron Collider (LHC), a particle accelerator aimed at exploring deeper into matter than ever before, is currently being constructed at CERN. Beam optics of the LHC, requires stringent control of the field quality of about 8400 superconducting ...
Masi, Alessandro
core  

Development of a Greek Oral health literacy measurement instrument: GROHL. [PDF]

open access: yesBMC Oral Health, 2020
Taoufik K   +4 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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