Results 201 to 210 of about 452,809 (247)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Measurement Properties of Instruments Assessing Digital Competence in Nursing: A Systematic Review. [PDF]

Appl Clin Inform
D'Agostino F, Erba I, Ammenwerth E, Robinzon V, Segal G, Harel N, Corvo E, Barkan R, Lewy H, Giannetta N.   +9 more
europepmc   +1 more source

Measurement instruments for assessing support needs of dementia caregivers: a COSMIN-based systematic review protocol. [PDF]

BMJ Open
Xiang C, Shen Y, Zhuo Y, Zhao X, Qiao B.
europepmc   +1 more source

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Measurement and Instrument Design

Journal of Wound, Ostomy & Continence Nursing, 2010
The soundness and robustness of research depend on the quality of data collection. An overview of the important considerations when developing an instrument for data collection is presented in this article. These considerations include theoretical issues fundamental to instrument development, conceptual model development, selection of instrument types,
Joyce, Pittman, Tamilyn, Bakas
openaire   +2 more sources

INSTRUMENTATION FOR THYROID MEASUREMENT*

The Journal of Clinical Endocrinology & Metabolism, 1953
THE problems arising from the use of radioactive iodine, both in the study of thyroid physiology and in its applications to routine thyroid tests, may be roughly divided into three categories. The first is the absolute determination of the quantity of radioactive iodine within a region in the body, e.g., the thyroid gland itself; the second is the ...
G L, BROWNELL, J B, STANBURY
openaire   +2 more sources

A cast measuring instrument

Medical & Biological Engineering, 1972
It has been established that the centre of the hard palate does not change after tooth loss and can be used as a reference area from which changes in the alveolar bone may be measured. A mechanical instrument was made for this purpose but, although giving reproducible results, the technique was tedious and time-consuming.
H F, Atkinson, A A, Grant
openaire   +2 more sources

INSTRUMENTAL MEASUREMENTS

Journal of Texture Studies, 1990
INSTRUMENTAL MEASUREMENTS: Resistance to Tear: An Instrumental Measure of the Cohesive Properties of Muscle Food Products. (Res. Note) J. H. MacNeil and M. G. MastINSTRUMENTAL MEASUREMENTS: A Small Sample Back Extrusion Test for Measuring Texture of Cooked Rice. V. G. Reyes, Jr. and V. K.
openaire   +1 more source