A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang +8 more
wiley +1 more source
Validation of a health literacy assessment tool in a nationwide population: a measurement invariance study using confirmatory factor analysis and multiple-group latent class analysis. [PDF]
Lee H, Han J.
europepmc +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Factor structure and measurement invariance of the Short Warwick-Edinbugh Mental Well-Being Scale (SWEMWBS) among adolescents and youths. [PDF]
Sarasjärvi KK +5 more
europepmc +1 more source
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv +11 more
wiley +1 more source
Factor structure and measurement invariance of the Turkish COA-IIIA among pre-service teachers in a centralized education system. [PDF]
Erdağ C, Karagöz S.
europepmc +1 more source
Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini +8 more
wiley +1 more source
Correction: Measurement invariance and cross-linguistic validation of the PSS-4 in university context: multidimensional analysis and associations with psychological and behavioral outcomes. [PDF]
Cañete-Massé C +4 more
europepmc +1 more source
This paper proposes a hierarchical reconfigurable metasurface architecture (HRMA) to achieve comprehensive electromagnetic parameter modulation and on‐demand polymorphic function switching. The reconfigurable metasurface is divided into a programmable core (PC) and scenario‐guided functional modules (FMs), exhibiting significant flexibility and ...
Lihao Zhu +11 more
wiley +1 more source
ADHD rating scale adaptation in Saudi Arabia: factor structure, measurement invariance, and normative data. [PDF]
Pierce CD +5 more
europepmc +1 more source

