Results 131 to 140 of about 2,250,709 (315)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Robust Estimation via Measurement Error Modeling
, 2005 We introduce a new method to robustifying inference that can be applied in any situation where a parametric likelihood is available. The key feature is that data from the postulated parametric models are assumed to be measured with error where the ...
Wang, Qiong
core
Model for Measuring Urban Development with a Socioeconomic Focus in Lima, Medellin and San Salvador
Urban ScienceThe measurement of urban development in Latin American cities has historically relied on one-dimensional models focused on GDP or density, which are insufficient to guide policies in heterogeneous and unequal contexts.
Fray L. Becerra-Suarez +3 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Time-varying coefficient models and measurement error [PDF]
, 2007 This thesis is concerned with presenting and developing modeling approaches which allow for a time-varying effect of covariates by using time-varying coefficients. The different approaches are compared in simulation studies.
Breitner, S., Breitner, Susanne
core
Open-loop mode resonance risk determination based on measurement model
电力工程技术The open-loop mode resonance theory is an important theoretical achievement to explain the mechanism of system instability caused by the grid connection of permanent magnet synchronous generator (PMSG), but the determination of the resonance risk of open-
Xingliang ZHANG +2 more
doaj +1 more source
Teacher Engagement as a Multidimensional Construct: Insights From a Measurement Model Analysis
Jurnal KependidikanThis study aims to evaluate teacher engagement as a multidimensional, reflective construct comprising four dimensions: academic support, emotional support, guidance support, and assessment support.
Nurkhairo Hidayati +3 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
An Information Model for Surface Metrology
, 2013 According to ISO standards, the specification and verification of surface texture includes an ordered set of operations. In order to reduce the specification uncertainty, it is of importance to model the significant information related to surface ...
Li, Tukun +3 more
core +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source