Results 51 to 60 of about 178,977,434 (287)

Measurement of Ultra-High Speed by Optical Multistage Cascade Frequency Reduction Technology

open access: yesApplied Sciences
In order to reduce the frequency of high-frequency Doppler signal light, the electronic bandwidth of a data acquisition system is reduced. This paper mainly describes the principle and experimental verification results of optical multistage cascade ...
Heli Ma   +14 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Aortic blood velocity measurement [PDF]

open access: yes
This image reflects a written document by L.H. Light and is titled Aortic blood velocity measurement by transcutaneous aortovelography and its clinical ...
Light, L.H.
core   +1 more source

Retrieval of Subsurface Velocities in the Southern Ocean from Satellite Observations

open access: yesRemote Sensing, 2023
Determining the dynamic processes of the subsurface ocean is a critical yet formidable undertaking given the sparse measurement resources available presently.
Liang Xiang   +8 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A New Method of Measuring the Velocity of Light [PDF]

open access: yesNature, 1938
IN determining the velocity of light by Fizeau's toothed wheel, the number of eclipses per second cannot be made more than about half a megacycle. Thus the method requires great distances. In two modern determinations, that of Karolus and Mittel-staedt at Leipzig in 1926, and that of Wilmer C. Anderson at Harvard in 1937, the toothed wheel was replaced
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Measurement Across the Sciences

open access: yes, 2023
This open access book proposes a conceptual framework for understanding measurement across a broad range of scientific fields and areas of application, such as physics, engineering, education, and psychology.
Mari, Luca, Maul, Andrew, Wilson, Mark
core   +1 more source

Verification of Spatial Heterodyne Spectral Velocimetry Technology Based on Solar Spectrum

open access: yesRemote Sensing
Deep space exploration is one of the key development directions in the aerospace field. With the significant increase in detection distance, the traditional space exploration methods may be ineffective due to effects such as signal energy attenuation and
Xiang Peng   +4 more
doaj   +1 more source

A Proposed Method for the Measurement of the Velocity of Light [PDF]

open access: yesNature, 1959
THE precision of optical methods of measuring the velocity c of electromagnetic radiation in free space is restricted by the upper limit of the frequency at which a light wave may be amplitude-modulated. Bergstrand1, in his recent measurements, used a modulation frequency of 10 Mc./sec. and consequently his base-lines were several km. long. The highest
openaire   +1 more source

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