Results 61 to 70 of about 178,977,434 (287)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Measurement of the group velocity of light in sea water at the ANTARES site [PDF]

Astroparticle Physics, 2012
The group velocity of light has been measured at eight different wavelengths between 385 nm and 532 nm in the Mediterranean Sea at a depth of about 2.2 km with the ANTARES optical beacon systems. A parametrisation of the dependence of the refractive index on wavelength based on the salinity, pressure and temperature of the sea water at the ANTARES site
S. Adrian Martinez, I. Al Samarai, A. Albert, M. Andre, M. Anghinolfi, G. Anton, S. Anvar, M. Ardid, A. C. Assis Jesus, Aca Jesus, T. Astraatmadja, J. J. Aubert, B. Baret, S. Basa, V. Bertin, S. Biagi, A. Bigi, C. Bigongiari, C. Bogazzi, M. Bou Cabo, B. Bouhou, M. C. Bouwhuis, J. Brunner, J. Busto, F. Camarena, CAPONE, Antonio, C. Carloganu, G. Carminati, J. Carr, S. Cecchini, Z. Charif, Ph Charvis, T. Chiarusi, M. Circella, H. Costantini, P. Coyle, C. Curtil, DE BONIS, Giulia, M. P. Decowski, I. Dekeyser, A. Deschamps, C. Distefano, C. Donzaud, D. Dornic, Q. Dorosti, D. Drouhin, T. Eberl, U. Emanuele, A. Enzenhofer, J. P. Ernenwein, S. Escoffier, FERMANI, PAOLO, M. Ferri, V. Flaminio, F. Folger, U. Fritsch, J. L. Fuda, S. Galata, P. Gay, K. Geyer, G. Giacomelli, V. Giordano, J. P. Gomez Gonzalez, K. Graf, G. Guillard, G. Halladjian, G. Hallewell, H. Van Haren, J. Hartman, A. J. Heijboer, Y. Hello, J. J. Hernandez Rey, B. Herold, J. Hossl, C. C. Hsu, M. De Jong, M. Kadler, O. Kalekin, A. Kappes, U. Katz, O. Kavatsyuk, P. Kooijman, C. Kopper, A. Kouchner, I. Kreykenbohm, V. Kulikovski, V. Kulikovskiy, R. Lahmann, P. Lamare, G. Larosa, D. Lattuada, D. Lefvre, D. Lefevre, G. Lim, D. Lopresti, D. Lo Presti, H. Loehner, S. Loucatos, S. Mangano, M. Marcelin, A. Margiotta, J. A. Martinez Mora, J. E. Mcmillan, A. Meli, T. Montaruli, L. Moscoso, H. Motz, M. Neff, E. Nezri, D. Palioselitis, G. E. Pvla, G. E. Pavalas, K. Payet, P. Payre, J. Petrovic, P. Piattelli, N. Picot Clemente, V. Popa, T. Pradier, E. Presani, C. Racca, C. Reed, G. Riccobene, C. Richardt, R. Richter, C. Rivire, C. Riviere, A. Robert, K. Roensch, A. Rostovtsev, J. Ruiz Rivas, M. Rujoiu, G. V. Russo, F. Salesa, D. F. E. Samtleben, P. Sapienza, F. Schock, J. P. Schuller, F. Schussler, F. Schussleraf, T. Seitz, R. Shanidze, SIMEONE, Francesco, A. Spies, M. Spurio, J. J. M. Steijger, Th Stolarczyk, A. Sanchez Losa, M. Taiuti, C. Tamburini, L. F. Thompson, S. Toscano, B. Vallage, V. Van Elewyck, G. Vannoni, M. Vecchi, P. Vernin, S. Wagner, G. Wijnker, J. Wilms, E. De Wolf, H. Yepes, D. Zaborov, J. D. Zornoza, J. Zuniga   +164 more
openaire   +8 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Development of portable microfading spectrometers for measurement of light sensitivity of materials [PDF]

, 2011
Microfading was originally designed for efficiently detecting extremely light-sensitive materials on objects in situ to determine the appropriate exhibition lighting conditions. By focusing an intense beam of light to a tiny submillimetre sized spot and
Lange, R, Townsend, Joyce H., Hyndes, P, Lange, Rebecca, Lucian, Andrei, Lucian, A, Townsend, JH, Hyndes, Paul, Liang, H, Liang, Haida, Hackney, S   +10 more
core  

Non-invasive velocity and volume fraction profile measurement in multiphase flows [PDF]

Multiphase flow is the simultaneous flow of two or more phases, in direct contact, and is important in the oil industry, e.g. in production wells, in sub-sea pipelines and during the drilling of wells.
Al-Hinai, Sulaiyam
core   +4 more sources

Detonation Velocity Measurement with Chirped Fiber Bragg Grating

Sensors, 2017
Detonation velocity is an important parameter for explosive, and it is crucial for many fields such as dynamic chemistry burn models, detonation propagation prediction, explosive performance estimation, and so on.
Peng Wei, Hao Lang, Taolin Liu, Dong Xia
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Object Tracking and Velocity Estimation Considering Deviation Due to LiDAR Illumination Surface

IEEE Access
For autonomous vehicles to effectively navigate urban environments where pedestrians and personal vehicles are in close proximity, it is crucial to accurately track and predict their positions and velocities to enable effective collision avoidance. Light
Takumi Okada, Kazuma Sekiguchi, Kenichiro Nonaka   +2 more
doaj   +1 more source