Results 171 to 180 of about 3,428,833 (292)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Corrigendum: Measurement Properties of Instruments Assessing Digital Competence in Nursing: A Systematic Review. [PDF]

Appl Clin Inform
D'Agostino F, Erba I, Ammenwerth E, Robinzon V, Segal G, Harel N, Corvo E, Barkan R, Lewy H, Giannetta N.   +9 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Measurement Properties of the Modified Incremental Step Test for Assessing Exercise Capacity in Individuals With Type 2 Diabetes. [PDF]

Physiother Res Int
de Carvalho LB, Ribas RC, de Alencar MCN, Pereira DAG, Trevizan PF, da Silva LP.   +5 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Measurement Properties and Minimal Detectable Change of the 6-Min Step Test for Estimating Cardiorespiratory Fitness in Hospitalized Individuals After Stroke. [PDF]

Physiother Res Int
Aguiar Pavesi RO, Boening A, Meyrelles SDS, Nascimento LR.   +3 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Measurement properties of the Spanish version of assessment of survivor concerns in cancer patients. [PDF]

Sci Rep
Calderon C, Lorenzo-Seva U, Ferrando PJ, Corral MJ, Oporto-Alonso M, Jiménez-Fonseca P.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Patient report outcome measures for Spanish-speaking adults with bronchiectasis: systematic review of measurement properties. [PDF]

Qual Life Res
Hamam-Alcober Y, Cimarras-Otal C, Sáez-Pérez JA, Herrero-Cortina B.   +3 more
europepmc   +1 more source