Results 131 to 140 of about 4,485,248 (291)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Measurement and Measurement Scales

open access: yes
This chapter examines measurement and measurement scales in business research. Measurement is defined in terms of the relationship to related factors and brief illustration of variables and types of data provided, differentiating between scientific terms, including concepts, constructs and operational definitions.
openaire   +3 more sources

Multicenter application of a nursing workload measurement scale in adult hospitalization units. [PDF]

open access: yesInt J Nurs Sci, 2022
Hellín Gil MF   +5 more
europepmc   +1 more source

Brand detachment: Conceptualization, antecedents and proposition of a measurement scale. [PDF]

open access: yes
Après avoir clarifié le concept de détachement de la marque, cette communication présente les résultats de notre première collecte de données. La première partie de ce papier conceptualise le phénomène de détachement de la marque : après une présentation
Perrin-Martinenq, Delphine
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Perceived communication effectiveness in implementation strategies: a measurement scale. [PDF]

open access: yesImplement Sci Commun, 2022
Zhao X   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Trunk Control Measurement Scale (TCMS): Psychometric Properties of Cross-Cultural Adaptation and Validation of the Spanish Version. [PDF]

open access: yesInt J Environ Res Public Health, 2023
López-Ruiz J   +7 more
europepmc   +1 more source

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