Results 111 to 120 of about 1,560,969 (307)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Service quality measurement in the internet context: A proposed model

, 2010
The survival of any organisation in a highly competitive environment depends on its ability to provide the best service quality to its existing customers as the quality of service is a key factor in the success of any organisation. It is well established
Alshawi, S, Albassam, T
core  

The Emotional States of the Consumer in Stores: The PA (Pleasure-Arousal) Adapted to the Algerian Context

Expert Journal of Marketing, 2016
The purpose of this paper is the proposal of a scale for measuring emotional states experienced within a point of sale, for non-English speaking consumers. Since the validity of the measuring instruments may affect the relevance and quality of managerial
Sabrina ELBACHIR, Abderrahmane CHENINI
doaj  

Validation de la version française de la Behavior and Instructional Management Scale

Mesure et Évaluation en Éducation, 2015
La Behavior and Instructional Management Scale (BIMS) développée par Martin et Sass (2010) permet de mesurer les pratiques et les croyances des enseignants en gestion de la classe.
Philippe Wanlin, Malika Revilloud
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

L’Échelle de la motivation générale à cultiver de saines habitudes de vie (ÉMGHV) : l’élaboration et l’évaluation initiale de l’instrument

Mesure et Évaluation en Éducation
Dans un contexte où le monde de l’éducation postsecondaire se mobilise pour augmenter la réussite et la diplomation, une attention accrue est actuellement portée sur la santé en tant que prédicteur de réussite scolaire.
Isabelle Cabot, Ph. D., Annie Bradette, M. Ed.   +1 more
doaj   +1 more source

Instrumentalising the Internal Control of Material Resources in an Industrial Enterprise to Provide Information Base for Management Decisions

Учёт. Анализ. Аудит
The article deals with the problems of instrumentalisation of the function of on-farm control of consumption of material resources in the production activities of industrial enterprises.
I. E. Mizikovskу
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The career satisfaction scale in context: A test for measurement invariance across four occupational groups

, 2015
This study analyzed the influence of the occupational context on the conceptualization of career satisfaction measured by the career satisfaction scale (CSS).
Daniel Spurk, Spurk, Daniel, Abele, Andrea E., Volmer, Judith, Andrea E. Abele, Judith Volmer   +5 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source