Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Psychometric properties of the Chinese version of the Athletic Identity Measurement Scale Plus: A confirmatory study on Chinese adolescents. [PDF]
Wang S +4 more
europepmc +1 more source
Development and validation of a quality of life measurement scale specific to hereditary hemorrhagic telangiectasia: the QoL-HHT. [PDF]
Le TTT +22 more
europepmc +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The anatomy of rage: conceptualization, operationalization, and validation of a new measurement scale. [PDF]
Michałkiewicz N, Strojny P, Strojny A.
europepmc +1 more source
Development and Validation of the Coping Capacity Measurement Scale of Public Health Emergencies in China. [PDF]
Zhang A, Yang H, Wu X, Luo X, Gao J.
europepmc +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
A new instrument for the measurement of very close tones
PAOLILLO, Alfredo +7 more
core +1 more source
Rasch Measurement Model creation in social science education has quickly spread to other educational domains, such as technical and engineering sciences. This research attempts to move testing and assessment in Laboratory Application in Science Education
Ocal, Zekiye Merve +1 more
core +1 more source
Patient empowerment outcomes in chronic disease care in Lebanon with validation of a measurement scale and associated determinants. [PDF]
Safwan J +12 more
europepmc +1 more source

