Results 81 to 90 of about 4,485,248 (291)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Knowledge Management & E-Learning: An International JournalIntellectual capital has aroused growing interest in higher education; however, one area for improvement in its study is how to measure it adequately. Therefore, it is necessary to have instruments based on current models of intellectual capital.
Yuranis Vargas-Atencio +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Quantum--Classical Interface Based on Single Flux Quantum Digital Logic
, 2017 We describe an approach to the integrated control and measurement of a large-scale superconducting multiqubit circuit using a proximal coprocessor based on the Single Flux Quantum (SFQ) digital logic family.
Liebermann, P. J. +6 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
SDN as Active Measurement Infrastructure [PDF]
, 2017 Active measurements are integral to the operation and management of networks, and invaluable to supporting empirical network research. Unfortunately, it is often cost-prohibitive and logistically difficult to widely deploy measurement nodes, especially ...
Beverly, Robert, Rye, Erik
core +1 more source
Measurement of the solar system acceleration using the Earth scale factor
, 2018 We propose an alternative method to detect the secular aberration drift induced by the solar system acceleration due to the attraction to the Galaxy centre.
Krásná, H., Titov, O.
core +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Institutions and the Value of Nonpoint Source Measurement Technology: Carbon Sequestration in Agricultural Soils [PDF]
The development of technologies for accurate field-scale carbon assessment allows the implementation of more efficient policies than can be implemented in their absence.
Kling, Catherine L. +2 more
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source