Results 81 to 90 of about 8,502,687 (299)

Socio-affective Presence in e-Learning: The theoretical reference model, the development and validation of the EMPSA e-Learning measurement scale

open access: yesMesure et Évaluation en Éducation
The article outlines the development and validation process of the measurement scale for socio-affective presence in e-learning. This scale was constructed based on the theoretical model of social presence in e-learning (Jézégou, 2022).
Annie Jézégou   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Translithospheric magma plumbing system fossilized in the Emeishan large igneous province

open access: yesCommunications Earth & Environment
Lighting up the magma plumbing system beneath a large igneous province (LIP) is challenging because the complex magma migration paths are often covered by flood basalts and sediments.
Sixue Wang   +9 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Cartesian approach to large scale co-ordinate measurement: InPlanT

open access: yes, 2014
A novel paradigm of coordinate measurement is presented, named InPlanT. The target application is the industrial measurement of large workpieces in harsh conditions, e.g. in aerospace industry.
PISANI, MARCO   +2 more
core  

Measurement and Monitoring of Microwave Reflection and Transmission Properties of Cement-Based Specimens [PDF]

open access: yes, 2001
The results of measurement and monitoring of reflection and transmission properties of cement-based specimens (blocks of mortar, concrete) during long time of their service lives, including hydration process, and different curing conditions at microwave ...
Atis, Cengiz Duran   +11 more
core   +1 more source

Report on nutrition and small-scale irrigation

open access: yes, 2023
The evidence on the potential for agricultural interventions to contribute to improved nutrition has grown considerably over the past decade. Numerous studies have explored both positive and negative effects of agriculture on nutrition and health.
Feed the Future Innovation Lab for Small Scale Irrigation
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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