Results 91 to 100 of about 3,537,805 (300)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Uncertainty in measurements by counting
, 2012 Counting is at the base of many high-level measurements, such as, for example, frequency measurements. In some instances the measurand itself is a number of events, such as spontaneous decays in activity measurements, or objects, such as colonies of ...
PENNECCHI, FRANCESCA ROMANA +1 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Generalized lambda distribution for the expression of measurement uncertainty
, 2006 The generalized lambda distribution family fits the probability distributions of a wide variety of data sets, including the most important distributions encountered in the measurement applications (normal, uniform, Student's t, U-shaped, exponential ...
PODESTA', Luca +2 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Uncertainty measures for evidential reasoning II: A new measure of total uncertainty
International Journal of Approximate Reasoning, 1993 In Part I [\textit{N. Pal}, \textit{J. Bezdek} and \textit{R. Hemasinha}, Int. J. Approx. Reasoning 7, No. 3/4, 165-183 (1992; Zbl 0769.68112)] we discussed limitations of two measures of global (non-fuzzy) uncertainty of \textit{M. Lamata} and \textit{S. Moral} [Measures of entropy in the theory of evidence, Trab. Estad. 3, No.
Nikhil R. Pal +2 more
openaire +3 more sources
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Uncertainty evaluation for Cs-137 in food by low-background α/β counter
Shipin yu jixieObjectiveTo improve the measurement accuracy of cesium-137 (Cs-137) content in food using low-background α/β measuring instruments.MethodsAn uncertainty analysis model for measuring Cs-137 in food was established based on the second method in GB 14883.10-
SUN Gongming +4 more
doaj +1 more source