Results 61 to 70 of about 243,524 (266)

Uncertainty as a Fairness Measure

Journal of Artificial Intelligence Research
Unfair predictions of machine learning (ML) models impede their broad acceptance in real-world settings. Tackling this arduous challenge first necessitates defining what it means for an ML model to be fair. This has been addressed by the ML community with various measures of fairness that depend on the prediction outcomes of the ML models, either at ...
Selim Kuzucu, Jiaee Cheong, Hatice Gunes, Sinan Kalkan   +3 more
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Uncertainty in measurement: A review of the procedures for determining uncertainty in measurement and its use in deriving the biological variation of the estimated glomerular filtration rate

Practical Laboratory Medicine, 2018
Procedures for assessing the uncertainty in measurement and estimates of biological variation are currently available for many measurands capable of direct analytical measurement.
Ian Farrance, Tony Badrick, Robert Frenkel   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Limiting Uncertainty Relations in Laser-Based Measurements of Position and Velocity Due to Quantum Shot Noise

Entropy, 2019
With the ongoing progress of optoelectronic components, laser-based measurement systems allow measurements of position as well as displacement, strain and velocity with unbeatable speed and low measurement uncertainty.
Andreas Fischer
doaj   +1 more source

Uncertainties in successive measurements

Physical Review A, 2013
Improvements in the prose (thanks to the referee). Version to appear in Phys. Rev. A.
Distler, Jacques, Paban, Sonia
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Uncertainty measures for evidential reasoning II: A new measure of total uncertainty

International Journal of Approximate Reasoning, 1993
In Part I [\textit{N. Pal}, \textit{J. Bezdek} and \textit{R. Hemasinha}, Int. J. Approx. Reasoning 7, No. 3/4, 165-183 (1992; Zbl 0769.68112)] we discussed limitations of two measures of global (non-fuzzy) uncertainty of \textit{M. Lamata} and \textit{S. Moral} [Measures of entropy in the theory of evidence, Trab. Estad. 3, No.
Nikhil R. Pal, James C. Bezdek, Rohan Hemasinha   +2 more
openaire   +2 more sources