Results 221 to 230 of about 1,342,843 (277)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Does baseline language ability predict response to early intervention for toddlers with early signs of autism? Evidence from a caregiver-mediated program. [PDF]

Front Hum Neurosci
Brian JA, Roth I, Zwaigenbaum L, Smith I, Sacrey LR, Bernardi K, MacWilliam S, Daoud S, Dowds E, Jilderda S, Osten S, Michelis A, Solish A.   +12 more
europepmc   +1 more source

MnI‐Functionalized Covalent Organic Framework as Efficient Electrocatalyst for CO2 Reduction in a Catholyte‐Free Zero‐Gap Electrolyzer

Advanced Functional Materials, EarlyView.
This work demonstrates the successful integration of a phenanthroline‐based 2D COF with MnI catalytic sites into a catholyte‐free membrane‐electrode‐assembly cell for CO2 electroreduction. The crystalline COF actively suppresses Mn⁰–Mn⁰ dimerization, achieving a turnover frequency of 617 h⁻¹ at 2.8 V (full‐cell potential), and enabling stable operation.
Laura Spies, Marcos Eduardo G. Carmo, Gonçalves J. Marrenjo, Stephan Reuther, Patrick Ganswindt, Antonio Otavio T. Patrocinio, Thomas Bein, Osmando F. Lopes, Jenny Schneider   +8 more
wiley   +1 more source

The association between early diagnosis of gestational diabetes and maternal-neonatal outcomes: a secondary analysis of the digest trial. [PDF]

Endocrine
Dib S, Luo N, Jones DL, Smith S, Taylor R, Murphy HR, Kusinski LC, Meek CL.   +7 more
europepmc   +1 more source

All‐in‐One Analog AI Hardware: On‐Chip Training and Inference with Conductive‐Metal‐Oxide/HfOx ReRAM Devices

Advanced Functional Materials, EarlyView.
An all‐in‐one analog AI accelerator is presented, enabling on‐chip training, weight retention, and long‐term inference acceleration. It leverages a BEOL‐integrated CMO/HfOx ReRAM array with low‐voltage operation (<1.5 V), multi‐bit capability over 32 states, low programming noise (10 nS), and near‐ideal weight transfer.
Donato Francesco Falcone, Victoria Clerico, Wooseok Choi, Tommaso Stecconi, Folkert Horst, Laura Bégon‐Lours, Matteo Galetta, Antonio La Porta, Nikhil Garg, Fabien Alibart, Bert Jan Offrein, Valeria Bragaglia   +11 more
wiley   +1 more source

Occupational Protection in Interventional Radiology. A Joint Guideline of the Cardiovascular and Interventional Radiological Society of Europe and the Society of Interventional Radiology. [PDF]

Cardiovasc Intervent Radiol
Miller DL, Vano E, Balter S, Kitahara CM, Wunderle KA, Reimer P, Fisher RF, Jones AK, Schueler BA, Paulo G, Efstathopoulos E, Bartal G.   +11 more
europepmc   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

A multimodal Bayesian network for symptom-level depression and anxiety prediction from voice and speech data. [PDF]

Sci Rep
Norbury A, Fairs G, Georgescu AL, Nour MM, Molimpakis E, Goria S.   +5 more
europepmc   +1 more source

Food Insecurity, Supplemental Nutrition Assistance Program Participation and Cognitive Function Among Middle-Aged and Older Adults: Longitudinal Evidence from the Health and Retirement Study. [PDF]

Nutrients
Luo Y, Li M, Zhang Z.
europepmc   +1 more source

Age-dependent and reversible refractive changes in 0-6 years old children associated with reduced outdoor activity: a six-year community-based study. [PDF]

Sci Rep
Xu L, Zhang Y, Yang C, Lan J, Li Z, Luo J, Guo Y, Hou X, Tian Z, Zeng J.   +9 more
europepmc   +1 more source