Results 41 to 50 of about 162,189 (243)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Fundamental Issues in Spectrum Measurement

open access: yesMetrology
Insight into spectrum measurement is provided regarding the possibility of achieving a unified definition of the measurand for important classes of phenomena, including periodic, transitory impulsive, stochastic stationary, and stochastic non-stationary ...
Giovanni Battista Rossi   +3 more
doaj   +1 more source

Research on green wave transit system based on 5G-V2X

open access: yesDianzi Jishu Yingyong, 2019
Combined with the fusion technology of MEC and C-V2X,a green wave transit system based on 5G vehicle network is studied, and relevant researches are made on the green wave transit model, application of MEC and collaborative control management.
Tian Liang, Zhang Yan, Xu Li
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez   +29 more
wiley   +1 more source

Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij   +11 more
wiley   +1 more source

RAZÕES PARA UM DESCREDENCIAMENTO EM EAD: O CASO UNITINS [PDF]

open access: yes, 2009
Objetiva compreender as razões que levaram o Ministério da Educação (MEC), a abrir um processo administrativo para o descredenciamento de cursos a distância oferecidos pela Unitins (Fundação Universidade Estadual do Tocantins). O presente texto analisa o
MAIA, MARIA ZOREIDE BRITTO
core  

From Bulk to Colloidal Nanocrystals: Top‐Down Synthesis of Highly Luminescent Cs2ZrCl6:Te4+ Double Perovskite Nanocrystals for X‐Ray Imaging

open access: yesAdvanced Functional Materials, EarlyView.
Top‐down ultrasonication produces highly emissive Cs2ZrCl6:Te4+ nanocrystals (NCs) with a PLQY of 65%, which is higher compared to that of the NCs synthesized by typical bottom‐up hot‐injection synthesis. The colloidal Cs2ZrCl6:Te4+ NCs have been found to be potential candidates for x‐ray scintillation imaging.
Yang Liu   +12 more
wiley   +1 more source

MEC-13-0531 (source data, and variable names and labels)

open access: yes, 2014
Source data, and variable names and labels, used for MEC-13-0531. Separate sheets refer to information related to: (1) adult trees, (2) offspring, (3) reproductive variables, (4) developed seeds per cone, (5 & 6) seed weight & embryo data, (7 ...
Juan L. García Castaño (3284634)   +6 more
core   +1 more source

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