Results 51 to 60 of about 162,189 (243)

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão   +5 more
wiley   +1 more source

A história em quadrinhos na aula de língua portuguesa como Segunda Língua (L2): relato de uma experiência com alunos surdos

open access: yesDomínios de Lingu@gem, 2016
Este trabalho faz parte do Projeto de Pesquisa Compreensão e Produção escrita em Língua Portuguesa, desenvolvido no Instituto Nacional de Educação de Surdos, e relata o ensino de Língua Portuguesa como L2 para graduandos surdos do curso de Pedagogia.
Fernanda Beatriz Caricari de Morais   +1 more
doaj   +1 more source

MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans [PDF]

open access: yes, 2016
The Caenorhabditis elegans DEG/ENaC proteins MEC-4 and MEC-10 transduce gentle touch in the six touch receptor neurons . Gain-of-function mutations of mec-4 and mec-4(d) result in a hyperactive channel and neurodegeneration in vivo.
Yushu Chen   +12 more
core   +1 more source

Hybridization of Gap Plasmons and Grating‐Coupled Surface Plasmon Polaritons in Metal Nanoparticle Cluster Arrays on a Mirror

open access: yesAdvanced Optical Materials, EarlyView.
Here we use a template‐assisted self‐assembly approach of metal colloids onto metal films to produce hybrid plasmonic metasurfaces that integrate nanoparticle‐on‐mirror cavities with periodic metal colloid arrays. The resulting coupling between gap plasmons and grating‐coupled surface plasmon polaritons enables programmable hybrid modes with tailored ...
Afroditi Koutsogianni   +6 more
wiley   +1 more source

A diminutive perivascular epithelioid cell tumor in the colon

open access: yesDEN Open
Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor. Some papers have reported that colonoscopy could be used to treat PEComa with a predominantly pedunculated polyp, whereas surgical intervention is often required for cases with ...
Naoki Sugimura   +7 more
doaj   +1 more source

Educação superior a distância no Brasil: uma construção consorciada e em rede

open access: yesLiinc em Revista, 2006
Este artigo descreve a experiência de implantação da política de fomento aos cursos de Graduação a Distância (EAD) no Brasil adotada pela Secretaria de Educação a Distância do Ministério da Educação (SEED/MEC) a partir de 2004.
Luiz Roberto Rodrigues Martins
doaj   +1 more source

PERSPECTIVAS ETNOGRÁFICAS E INFÂNCIAS INDÍGENAS: MODOS DE SER DAS CRIANÇAS ASURINÍ E BANIWA

open access: yesRevista da Fundarte, 2020
Este artigo trata da experiência de pesquisa com crianças em dois contextos socioculturais distintos (MIRANDA, 2014; MARQUI, 2017), onde a observação etnográfica de questões semelhantes contribui para debates teóricos específicos.
Amanda Rodrigues Marqui   +1 more
doaj   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

open access: yesAdvanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu   +7 more
wiley   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Low-Grade Mucoepidermoid Carcinoma: Rare Pulmonary Tumor with Excellent Prognosis

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth
Mucoepidermoid carcinoma (MEC) of the lung is a rare form of lung cancer that is classified into low grade and high grade based on histological features.
Rupali Bavikar   +4 more
doaj   +1 more source

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