Results 51 to 60 of about 123,451 (303)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Evolutionary Origin of the Staphylococcal Cassette Chromosome mec (SCC mec ) [PDF]

open access: yes, 2017
Several lines of evidence indicate that the most primitive staphylococcal species, those of the Staphylococcus sciuri group, were involved in the first stages of evolution of the staphylococcal cassette chromosome mec
Peter Damborg   +23 more
core   +1 more source

EEL-1 maintains the normal PVD dendrite through MEC-3. [PDF]

open access: yes, 2023
(A) Representative confocal images showing the PVD dendrite pattern in mec-3(deExon2), mec-3(deExon2); eel-1(wy50785), mec-3(deExon2); PVD::mec-3(deExon2) cDNA, mec-3(wy50748), mec-3(wy50748); PVD::mec-3(deExon2), mec-3(wy50748); eel-1(wy50786).
Jianxin Xie (668046)   +4 more
core   +1 more source

Research on green wave transit system based on 5G-V2X

open access: yesDianzi Jishu Yingyong, 2019
Combined with the fusion technology of MEC and C-V2X,a green wave transit system based on 5G vehicle network is studied, and relevant researches are made on the green wave transit model, application of MEC and collaborative control management.
Tian Liang, Zhang Yan, Xu Li
doaj   +1 more source

MEO: An Enhanced MEC Orchestrator for Federated and Distributed MEC Systems

open access: yesGLOBECOM 2024 - 2024 IEEE Global Communications Conference
Resource distribution among diverse administrative domains, network operators, and geographical locations across the edge-to-cloud continuum requires suitable communication and management and orchestration (MANO) mechanisms among orchestration domains.
Palomares, Javier   +4 more
openaire   +2 more sources

dRG-MEC: Decentralized Reinforced Green Offloading for MEC-enabled Cloud Network

open access: yes2023 19th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob), 2023
Multi-access-Mobile Edge Computing (MEC) is a promising solution for computationally demanding rigorous applications, that can meet 6G network service requirements. However, edge servers incur high computation costs during task processing. In this paper, we proposed a technique to minimize the total computation and communication overhead for optimal ...
Asad Aftab, Semeen Rehman
openaire   +2 more sources

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Prescriptive Analytics for MEC Orchestration [PDF]

open access: yes2018 IFIP Networking Conference (IFIP Networking) and Workshops, 2018
Orchestrating network and computing resources in Mobile Edge Computing (MEC) is an important item in the networking research agenda. In this paper, we propose a novel algorithmic approach to solve the problem of dynamically assigning base stations to MEC facilities, while taking into consideration multiple time-periods, and computing load switching and
Ceselli, Alberto   +5 more
openaire   +4 more sources

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

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