Results 91 to 100 of about 47,337 (212)

Emerging role of metagenomic next‐generation sequencing in infectious disease diagnostics: Clinical integration and future directions

mLife, Volume 5, Issue 2, Page 148-163, April 2026.
Abstract Infectious disease diagnostics has been transformed by metagenomic next‐generation sequencing (mNGS), an unbiased approach that detects bacteria, viruses, fungi, and parasites in a single assay. By sequencing all nucleic acids in a sample, mNGS overcomes the narrow detection scope and slow turnaround of conventional tests, substantially ...
Tingting Fang, Feifei Yuan, Yu Chen, Na Li, Yao Zhang, Haixia Liu, Xingchen Liu, Qing Miao, Bijie Hu   +8 more
wiley   +1 more source

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

Veterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling, Elisa Peh, Hilke Oltmanns, Jessica Meissner, Sophie Kittler, Christina Puff, Jutta Verspohl, Mathias Müsken, Madeleine Plötz, Andrea Vanessa Volk   +9 more
wiley   +1 more source

Direct Detection of Methicillin-Resistant Staphylococcus Aureus in Sputum Specimens from Patients with Hospital-Associated Pneumonia Using a Novel Multilocus Pcr Assay

Pathogens, 2015
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of hospital-associated pneumonia (HAP). The rapid identification of MRSA would be beneficial for early diagnosis.
Zeng-Guang Huang, Xing-Zheng Zheng, Jing Guan, Shu-Nian Xiao, Chao Zhuo   +4 more
doaj   +1 more source

Genome editing technologies to fight infectious diseases [PDF]

, 2017
Genome editing by programmable nucleases represents a promising tool that could be exploited to develop new therapeutic strategies to fight infectious diseases.
Barzon, Luisa, Pal\ue3\ub9, Giorgio, Trevisan, Marta   +2 more
core   +1 more source

Molecular detection of mecA gene from Methicillin Resistant Coagulase Negative Staphylococci

Journal of Microbiology and Biotechnology Research, 2017
In the present research, a total of 27 Wound swab samples were collected for the isolation of Methicillin Resistant-Coagulase Negative Staphylococci. Out of these, 3.7% of the samples have been shown the presence of Methicillin Resistant-CoagulaseNegative Staphylococci (MR-CoNS). The preliminary coagulase activity has been identified by Coagulase slide
Arun Thangave, Chandrasekaran Rajamanickam, Omprakash Sahu, Saravanan Ponnappan, Gezahegn Abawa, Abenezer Tadele   +5 more
openaire   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, Volume 12, Issue 1, Page 65-85, Spring 2026.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Molecular characterization of mecA gene in Methicillin-Resistant Staphylococcus aureus

University of Thi-Qar Journal of Science, 2016
 objectives: It is clear now that methicillin-resistant Staphylococcus aureus (MRSA) strains considered as one of the most bacteria responsible for different diseases among humans and animals. The present study aimed todetect the molecular profile of methicillin-resistant S.
openaire   +4 more sources

Screening of Staphylococcus aureus isolates for mecA and mecC genes carriage

Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2016
Metisilin-direncli Staphylococcus aureus (MRSA) hastane enfeksiyonlari ve farkli sistemik enfeksiyonlara yol acan onemli bir patojendir. MRSA olusumu stafilokok kaset kromozom mec (SCCmec) uzerinde yer alan mecA geni edinimi ile olusur. MecC geni, mecA genine ~69 DNA benzerlik gosteren bir mecA geni homologudur. MecC geni pozitif S.
DOĞAN, Eyüp, KILIÇ, Abdullah, TÜRÜTOĞLU, Hülya, ÖZTÜRK, Dilek, TÜRKYILMAZ, Süheyla   +4 more
openaire   +3 more sources

Isolation, Antibiogram and Factors Associated With Staphylococcus aureus From Fish at the Landing Site and Selected Restaurants in Central Gondar, Ethiopia: One Health Approach

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
This study identified Staphylococcus aureus in 26% of fish, hand and knife samples from Gondar, Ethiopia, with high multidrug resistance. Findings highlight unsafe handling practices and recommend improved hygiene, regular monitoring and targeted antibiotic use to reduce contamination risks and protect public health through a One Health approach ...
Misganaw Tezera Ayele, Asnakew Mulaw Berihun, Ambaye Kenubih Worku, Mengesha Ayehu Getnet   +3 more
wiley   +1 more source

Targeted inhibition of mecA and agrA genes in clinical MRSA isolates by natural bioactive compounds

Frontiers in Microbiology
IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) colonization in the nasal nares significantly contributes to hospital-acquired infections.
V. Vinodhini, M. Kavitha
doaj   +1 more source