Results 41 to 50 of about 2,899 (170)

Beyond the Wild MRSA: Genetic Features and Phylogenomic Review of mecC-Mediated Methicillin Resistance in Non-aureus Staphylococci and Mammaliicocci

open access: yesMicroorganisms, 2023
Methicillin resistance, mediated by the mecA gene in staphylococci and mammaliicocci, has caused tremendous setbacks in the use of antibiotics in human and veterinary medicine due to its high potential of presenting the multidrug resistance (MDR ...
Idris Nasir Abdullahi   +9 more
doaj   +1 more source

A novel hybrid SCCmec-mecC region in Staphylococcus sciuri [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2013
Methicillin resistance in Staphylococcus spp. results from the expression of an alternative penicillin-binding protein 2a (encoded by mecA) with a low affinity for β-lactam antibiotics. Recently, a novel variant of mecA known as mecC (formerly mecALGA251) was identified in Staphylococcus aureus isolates from both humans and animals.
Harrison, Ewan M.   +11 more
openaire   +5 more sources

Preparation of Antiproliferative Terpene-Alkaloid Hybrids by Free Radical-Mediated Modification of ent-Kauranic Derivatives

open access: yesMolecules, 2021
A convenient strategy for molecular editing of available ent-kauranic natural scaffolds has been developed based on radical mediated C–C bond formation.
Elena Pruteanu   +6 more
doaj   +1 more source

A thermoplastic microfluidic platform with integrated electrospun scaffolds for assessing brain cell‐specific drug selectivity

open access: yesVIEW, EarlyView.
Schematic representation of the microfluidic platform with its advantages. Abstract A major challenge in pharmacology is the limited selectivity of therapeutic compounds toward specific tissues or cells. Drugs often distribute systemically before reaching the intended site of action, affecting nontarget cells and potentially reducing efficacy or ...
Maria Testa   +8 more
wiley   +1 more source

Performance of the BioFire FilmArray Pneumonia Panel Plus Compared to Standard Microbiology in Lung Transplant Donor and Recipient Samples: A Prospective Cohort Study

open access: yesTransplant Infectious Disease, EarlyView.
A prospective study demonstrating that the BioFire Pneumonia Panel Plus shows substantial concordance with culture in donor samples and moderate concordance in recipient samples, supporting its potential role in guiding perioperative antibiotic prophylaxis in lung transplantation.
Andrea Lombardi   +19 more
wiley   +1 more source

First report of methicillin-resistant Staphylococcus aureus carrying the mecC gene in human samples from Iran: prevalence and molecular characteristics

open access: yesNew Microbes and New Infections, 2021
There is a lack of information concerning mecC clinical methicillin-resistant Staphylococcus aureus (MRSA) strains throughout the world. In the present survey, 345 MRSA strains were characterized by antimicrobial susceptibility testing and staphylococcal
M. Goudarzi   +4 more
doaj   +1 more source

Exploring Challenges and Co‐Developing a Nutritional Resource for Antenatal Care: A Participatory Stakeholder Engagement Study With Midwives and Public Involvement

open access: yesHealth Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Background It is important that midwives discuss good nutrition and optimal weight during antenatal appointments, yet this rarely happens. Earlier research suggests that limited time, plus insufficient knowledge and skills are barriers to this.
Julie Abayomi   +4 more
wiley   +1 more source

First report of mecC MRSA in human samples from Austria: molecular characteristics and clinical data

open access: yesNew Microbes and New Infections, 2015
Reports of mecC methicillin-resistant Staphylococcus aureus (MRSA) strains have been published from several European countries. We describe the first six mecC MRSA isolates of human origin from Austria and report the application of a rapid PCR test ...
H. Kerschner   +4 more
doaj   +1 more source

‘Making every contact count’ with patients with musculoskeletal conditions: a qualitative exploration of acceptability to physiotherapists

open access: yesBMC Health Services Research, 2023
Aim To qualitatively explore physiotherapists’ experiences and acceptability of implementing ‘Making Every Contact Count Healthy Conversation Skills’ (MECC HCS) in routine practice with patients with musculoskeletal (MSK) conditions. Methods This article
Amelia Parchment   +5 more
doaj   +1 more source

A Review of the Management of Obesity in Primary Care

open access: yesClinical Obesity, Volume 16, Issue 1, February 2026.
ABSTRACT This review highlights the important role primary care plays in obesity management, using England as an example. It includes a comprehensive summary of current management and referral options for primary care clinicians, a discussion of the most up‐to‐date clinical guidelines for the use of GLP‐1 receptor agonists in England, and the evolving ...
H. M. Parretti   +7 more
wiley   +1 more source

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