Results 101 to 110 of about 3,550,619 (297)

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Friction on Mechanical Mechanisms

open access: yes
Friction is a critical factor influencing the performance, efficiency, and longevity of mechanical systems. This paper presents a comprehensive study on the impact of friction within various mechanical mechanisms, encompassing both theoretical analysis and experimental validation.
Avdhut Gujar, A. Awasare
openaire   +2 more sources

Mechanical Metamaterials and Their Engineering Applications

open access: yesAdvanced Engineering Materials, 2019
In the past decade, mechanical metamaterials have garnered increasing attention owing to its novel design principles which combine the concept of hierarchical architecture with material size effects at micro/nanoscale.
J. U. Surjadi   +6 more
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Mechanics of Schrodinger mechanics

open access: yes, 2004
Small perturbations of ideal turbulence obey the Schrodinger equation. Microscopically, the perturbation of turbulence corresponds to formation of small amplitude helices on straight vortex filaments. A helix behaves in the vorticity field of the fluid as a spin particle in the Stern-Gerlach experiment.
openaire   +2 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Mechanics [PDF]

open access: yesJournal of the Franklin Institute, 1888
n ...
openaire   +2 more sources

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