Results 101 to 110 of about 3,694,494 (318)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Comparison of Properties of Polymer Composite Materials Reinforced with Carbon Nanotubes
Archives of Metallurgy and Materials, 2015 Carbon nanotubes because of their high mechanical, optical or electrical properties, have found use as semiconducting materials constituting the reinforcing phase in composite materials.
Zygoń P. +3 more
doaj +1 more source
, 2010 Examination and practice in the application of many mechanical design elements, including control components. Students working in groups design, fabricate, and test prototype devices in response to requests from industrial sponsors.
Smith, Amy, Frey, Daniel
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The Mechanics of Fast-Start Performance of Pike Studied Using a Mechanical Fish [PDF]
, 2019 A northern pike (Esox lucius) is capable of achieving a maximum instantaneous acceleration of 25g, far greater than that achieved by any manmade vehicle.
Modarres-Sadeghi, Yahya +3 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Allergy and Asthma Proceedings, 1998 Mast cell degranulation leads to the release of histamine and a host of other mediators. However, histamine remains preeminent in proffering the vexatious symptoms of allergic rhinitis including itching, sneezing, dripping, and congestion. The mechanisms of symptom production in rhinitis will be reviewed with an eye toward effects on mucosal resident ...
openaire +2 more sources
Mechanical ventilation for the non-critical care trained practitioner. Part 1
, 2020 There have been a recent shortage of both critical care physicians and respiratory therapists with training in mechanical ventilation that is accentuated by the recent COVID-19 crisis.
Rebecca Shimabukuro, Ehab G. Daoud
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The journal of the Amateur Mechanical Society.
, 1871 Mode of access ...
Amateur Mechanical Society.
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