Results 71 to 80 of about 899,308 (256)

Usage of a statistical method of designing factorial experiments in the mechanical activation of a complex CuPbZn sulphide concentrate [PDF]

Acta Montanistica Slovaca, 2003
Mechanical activation belongs to innovative procedures which intensify technological processes by creating new surfaces and making a defective structure of solid phase.
BalហPeter, Godoèíková Erika, Leško Michal   +2 more
doaj  

Activation of Extracellular-signal Regulated Kinase (ERK1/2) by Fluid Shear is Ca\u3csup\u3e2+\u3c/sup\u3e- and ATP-dependent in MC3T3-E1 Osteoblasts [PDF]

, 2008
To determine the role of Ca2+ signaling in activation of the Mitogen-Activated Protein Kinase (MAPK) pathway, we subjected MC3T3-E1 pre-osteoblastic cells to inhibitors of Ca2+ signaling during application of fluid shear stress (FSS).
Duncan, Randall L., Geist, Derik J., Genetos, Damian C., Ke, Hua Zhe, Li, Jiliang, Liu, Dawei, Shao, Ying, Turner, Charles H.   +7 more
core   +1 more source

Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins. [PDF]

, 2015
GIV/Girdin is a multimodular signal transducer and a bona fide metastasis-related protein. As a guanidine exchange factor (GEF), GIV modulates signals initiated by growth factors (chemical signals) by activating the G protein Gαi.
Ghosh, Pradipta, Kabir, Firooz, Kalogriopoulos, Nicholas, Lo, I-Chung, Lopez-Sanchez, Inmaculada, Midde, Krishna K, Wang, Honghui   +6 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Alkaline leaching of mechanically activated berthierite and boulangerite [PDF]

Acta Montanistica Slovaca, 2006
In this study, changes in the surface area, morphology and the leachability of antimony from mechanically activated berthierite FeSb2S4, boulangerite - Pb5Sb4S11 by a high-energy planetary mill were investigated.
Marcela Achimovičová, Peter Baláž
doaj  

Zeolit ve mermer tozu kullanılarak üretilen CAS seramiklere mekanik aktivasyonun etkisi

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
Bu çalışmada CAS (CaO-Al2O3-SiO2)seramikleri zeolit, mermer tozu ve alümina tozları kullanılarak; 400 dev/dk ve600 dev/dk hızlarında mekanik aktivasyon ile üretilmiştir. Aktive edilen tozlarpres yardımı ile şekillendirildikten sonra 1000oC-1200oCsıcaklık
Zafer Yavuz Merkit, Cansu Özarslan, Bahadır Aydın, Nil Toplan   +3 more
doaj   +1 more source

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. [PDF]

, 2020
Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Basbaum, Allan I, Braz, Joao M, Guan, Zhonghui, Hamel, Katherine A, Leff, Jacqueline, Liu, Hongju, Morvan, Maelig G, Yu, Stephen, Yu, Xiaobing   +8 more
core   +1 more source

Glucocorticoid receptor signalling activates YAP in breast cancer [PDF]

, 2017
The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo pathway leads to aberrant activation of the transcription co-activator YAP ...
Bertolio, Rebecca, Bicciato, Silvio, Cappuzzello, Elisa, Del Sal, Giannino, Forcato, Mattia, Ingallina, Eleonora, Mano, Miguel, Marotta, Carolina, Neri, Carmelo, Rosato, Antonio, Ruggeri, Naomi, Sorrentino, Giovanni, Zannini, Alessandro   +12 more
core   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Dynamic characteristics and processing of fillers in polyurethane elastomers for vibration damping applications [PDF]

, 2011
Polyurethane elastomers have the potential of being used to reduce vibrational noise in many engineering applications. The performance of the elastomer is directly related to matching the nature of the mechanical loss characteristics to the frequency and
A R Mackintosh, Eyring H., Fu W. H., Kremer F., R A Pethrick, W M Banks   +5 more
core   +1 more source