Results 81 to 90 of about 898,493 (283)
Akt: a new activation mechanism [PDF]
Cell Research, 2014 Akt phosphorylation at S473 and T308 has been believed to be the prerequisites for its activation for years. Now, new phosphorylation event on Akt is identified and can trigger Akt activation and lead to its downstream oncogenic events.
Yuan, Gao, Asad, Moten, Hui-Kuan, Lin
openaire +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Extraction of organic compounds from brown coal [PDF]
Acta Montanistica Slovaca, 2005 The paper presents the study on the extraction of organic compounds (low-molecular weight - diterpenes, high-molecular weight - fullerenes and humic acids) from Handlová brown coal and pyrolytic soot.
Slavomír Hredzák +5 more
doaj
Nauka ta progres transportu, 2014 Purpose. Prospectivity assessments of the nano-materials usage in construction technologies at the same time meeting the requirements of environmental safety and rational use of the natural resources. Methodology.
H. P. Ivanova, O. I. Trufanova
doaj +1 more source
Activation of Extracellular-signal Regulated Kinase (ERK1/2) by Fluid Shear is Ca\u3csup\u3e2+\u3c/sup\u3e- and ATP-dependent in MC3T3-E1 Osteoblasts [PDF]
, 2008 To determine the role of Ca2+ signaling in activation of the Mitogen-Activated Protein Kinase (MAPK) pathway, we subjected MC3T3-E1 pre-osteoblastic cells to inhibitors of Ca2+ signaling during application of fluid shear stress (FSS).
Duncan, Randall L. +7 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Usage of a statistical method of designing factorial experiments in the mechanical activation of a complex CuPbZn sulphide concentrate [PDF]
Acta Montanistica Slovaca, 2003 Mechanical activation belongs to innovative procedures which intensify technological processes by creating new surfaces and making a defective structure of solid phase.
Balá Peter +2 more
doaj
Ab initio mechanical response: internal friction and structure of divacancies in silicon
, 2004 This letter introduces ab initio study of the full activation-volume tensor of crystalline defects as a means to make contact with mechanical response experiments. We present a theoretical framework for prediction of the internal friction associated with
Arias, T. A., Roundy, D., Ustunel, H.
core +1 more source
Mechanical activation influence on the morphological properties of La[2]O[3]-TiO[2]-B [PDF]
, 2000 The influence of mechanical activation of the powder mixture used to obtain the high-perfomance cathode for accelerating engineering with the SHS-method has been explored. The mechanically processed mixtures have been morphologically analyzed.
O Dolmatov +9 more
core +1 more source
A mechanism for active hearing [PDF]
Current Opinion in Neurobiology, 2007 The remarkable sensitivity, frequency selectivity, and nonlinearity of the cochlea have been attributed to the putative 'cochlear amplifier', which consumes metabolic energy to amplify the cochlear mechanical response to sounds. Recent studies have demonstrated that outer hair cells actively generate force using somatic electromotility and active hair ...
Tianying, Ren, Peter G, Gillespie
openaire +2 more sources