Results 81 to 90 of about 1,395,295 (247)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Variational integrators for degenerate Lagrangians, with application to point vortices [PDF]
, 2002 We develop discrete mechanics and variational integrators for a class of degenerate Lagrangian systems, and apply these integrators to a system of point vortices. Excellent numerical behavior is observed.
Marsden, Jerrold E., Rowley, Clarence W.
core
, 2014 We study the geometrically nonlinear behavior of uniformly compressed tensegrity prisms, through fully elastic and rigid--elastic models. The presented models predict a variety of mechanical behaviors in the regime of large displacements, including an ...
Amendola, Ada +2 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Self-supervised probabilistic models for exploring shape memory alloys
npj Computational MaterialsRecent advancements in machine learning (ML) have revolutionized the field of high-performance materials design. However, developing robust ML models to decipher intricate structure-property relationships in materials remains challenging, primarily due ...
Yiding Wang +6 more
doaj +1 more source
Mechanical behavior of robocast alumina [PDF]
, 1998 Direct fabrication of alumina parts by robocasting was completed. This method is based on three-dimensional deposition of binderless aqueous alumina slurries. Parts were made with different deposition paths and mechanical·testing performed·to determine the effects •of bead alignment. Properties were also compared to.
Denham, H. B. +3 more
openaire +2 more sources
The role of energy in deformation [PDF]
Necking, yield, and plastic flow in electrical analogs of mechanical systems with respect to energy conversion effects on mechanical behavior of various ...
Gruntfest, I. J.
core +1 more source
, 2007 We numerically study the jamming transition in particulate systems with attraction by investigating their mechanical response at zero temperature. We find three regimes of mechanical behavior separated by two critical transitions--connectivity and ...
Corey S. O’Hern +4 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source