Results 51 to 60 of about 198,328 (259)

Methods for Increasing Power Efficiency of Heating Furnaces Applied in Metallurgical and Mechanical Engineering Industries

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2011
The paper analyzes experimental data and results of balance tests of two continuous heating furnaces applied in mechanical engineering and metallurgical industries.
M. L. German, S. M. Kabishov, A. A. Oznobishin   +2 more
doaj  

Tunable Plug‐and‐Play Meta‐Nanogenerator Materials for Multi‐Range Force Measurements

Advanced Science
Accurate assessments of mechanical forces are crucial for the design, operation and maintenance of long‐lasting engineering systems. Conventional force sensors that are deployed in engineering applications suffer from multiple shortcomings including high
Roshira Premadasa, Pouya Almasi, Samriddhi Ghimire, Wenkui Dong, Chenjie Zhang, Pengcheng Jiao, Qianyun Zhang   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The use of mechanically activated micronized coal in thermal power engineering

Thermal Science, 2016
Coal is one of the main energy resources and development of new promising technologies on its basis is certainly topical. This article discusses the use of new technology of gas and fuel oil replacement by mechanically activated micronized coal in power engineering: ignition and stabilization of pulverized coal flame combustion, as well as ...
Burdukov, A. P., Butakov, E. B., Popov, V. I., Chernetskiy, M. Yu., Chernetskaya, N. S.   +4 more
openaire   +4 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A novel transparent cabin used in the classroom during the coronavirus pandemic: a CFD analysis

Journal of Engineering and Applied Science
A coronavirus family is a diverse group of many viruses. Coronavirus disease 19 (COVID-19) spreads when an infected person breathes out droplets and very small particles that contain the virus.
Mennatullah ElShimi, Samy M. Morcos, Galal M. Mostafa, Essam E. Khalil, Gamal A. El-Hariry, Ahmed ElDegwy   +5 more
doaj   +1 more source

Engineering of Impulse Mechanism for Mechanical Hander Power Tools

IOP Conference Series: Materials Science and Engineering, 2018
The solution to the problem of human security in cities should be considered on the basis of an integrated and multidisciplinary approach, including issues of security and ecology in the application of technical means used to ensure the viability and development of technocracy.
openaire   +1 more source