Results 101 to 110 of about 2,474,940 (289)
Most studies on granular physics have focused on dry granular media, with no liquids between the grains. However, in geology and many real world applications (e.g., food processing, pharmaceuticals, ceramics, civil engineering, constructions, and many ...
Albert I +93 more
core +3 more sources
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Investigation study of integrated vocational guidance on work readiness of mechanical engineering vocational school students. [PDF]
Inderanata RN, Sukardi T.
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Assessment technologies of rail systems' structural adequacy - A review from mechanical engineering perspectives. [PDF]
Hua X, Zatar W, Gadedesi A, Liao Z.
europepmc +1 more source
Polyaryl ethers and related polysiloxane copolymer molecular coatings preparation and radiation degrdation [PDF]
Poly(arylene ether sulfones) comprise a class of materials known as engineering thermoplastics which have a variety of important applications. These polymers are tough, rigid materials with good mechanical properties over a wide temperature range, and ...
Hedrick, J. L. +5 more
core +1 more source
Problem-based learning in facilities planning: a pilot implementation [PDF]
In Universiti Teknologi Malaysia, Problem Based Learning (PBL) is proposed as an alternative to lectures in moulding engineering graduates to acquire attributes that are required to excel in today’s k-economy.
Abd. Hamid, Mohd. Kamaruddin +3 more
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Limits of dropwise condensation heat transfer on dry nonwetting surfaces
Summary: Surface condensation is ubiquitous in applications such as power generation and desalination. Nonwetting surfaces have been studied extensively for their dropwise condensation potential with reports of dramatic improvements relative to the ...
Sandeep Hatte, Ranga Pitchumani
doaj +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source

