Results 271 to 280 of about 2,534,317 (363)

Technical High School Education (and Education in Mechanical Engineering) Present Status and Future Problems

, 1976
Shigematsu OHKI
openalex   +2 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Supervised Machine Learning and Physics Machine Learning approach for prediction of peak temperature distribution in Additive Friction Stir Deposition of Aluminium Alloy. [PDF]

PLoS One
Mishra A, Jatt V, Sefene EM, Salunkhe S, Cep R, Abouel Nasr E.   +5 more
europepmc   +1 more source

Causal Impressions of Japan in the Eyes of a British Mechanical Engineering Researcher

, 1976
Bradley Dodd, Hideaki Kudo
openalex   +2 more sources

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Research on the influence of waterproof layer on lining mechanical performance under early temperature load. [PDF]

PLoS One
Sun M, Guan Z, Guo C, Xi X, Tian S.
europepmc   +1 more source

Mechanical Engineering at a Time of Rapid Growth in LSI Technology

, 1976
Yasundo Takahashi
openalex   +2 more sources

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Retraction notice to "Deep retrofitting toward net zero energy building in the Mediterranean region: A case study of Albania" [Heliyon 10 (2024) e35174]. [PDF]

Heliyon
Malka L, Dervishi I, Owolabi AB, Abdullahi Y, Suh D, Aliaj B, Zeqo M, Dervishi R.   +7 more
europepmc   +1 more source

Present and Future of Gear Technology(<Special Issue>Future Development of Mechanical Engineering and Industries)

, 1979
Jiro ISHIKAWA
openalex   +2 more sources