Results 261 to 270 of about 5,213 (312)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

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Scientific and technical research in the field of mechanical engineering and transport

2023
У монографії розроблено аналітичний метод розрахунку теплових полів у процесі заливки ливарної форми та кристалізації металу, наведено методологію визначення динамічних сил та параметрів напружено-деформованого стану напіввагона при розвантаженні роторним вагоноперекидачем, досліджено конструкційні параметри елементів сошника для посіву просапних ...
Rostyslav Liutyi, Ruslan Vizniak, Dmytro Artemenko, Volodymyr Onopa, Andrii Kashkanov   +4 more
openaire   +1 more source

Visualization of the Rotary Engine Oil Transport Mechanisms

SAE International Journal of Engines, 2014
<div class="section abstract"><div class="htmlview paragraph">The rotary engine provides high power density compared to piston engine, but one of its downside is higher oil consumption. In order to better understand oil transport, a laser induced fluorescence technique is used to visualize oil motion on the side of the rotor during engine ...
Mathieu Picard, Hiroyuki Hidaka, Tian Tian, Takayuki Nishino, Eiji Arai, Masaki Ohkubo   +5 more
openaire   +1 more source

An Integrated Finite-Element Approach to Mechanics, Transport and Biosynthesis in Tissue Engineering

Journal of Biomechanical Engineering, 2004
A finite-element approach was formulated, aimed at enabling an integrated study of mechanical and biochemical factors that control the functional development of tissue engineered constructs. A nonlinear biphasic displacement-velocity-pressure description was combined with adjective and diffusive solute transport, uptake and biosynthesis.
Sengers, Bram G., Oomens, Cees W., Baaijens, Frank P.   +2 more
openaire   +3 more sources

Multidrug transport by ATP binding cassette transporters: a proposed two-cylinder engine mechanism

Research in Microbiology, 2001
The elevated expression of ATP binding cassette (ABC) multidrug transporters in multidrug-resistant cells interferes with the drug-based control of cancers and infectious pathogenic microorganisms. Multidrug transporters interact directly with the drug substrates.
van Veen, HW, Higgins, CF, Konings, WN
openaire   +3 more sources

Mechanical Engineering Problems in Marine Transport

Proceedings of the Institution of Mechanical Engineers, 1939
This, and the following papers by Mr. Stanier, Mr. Ottaway, and Mr. Gouge, were to have been read at the Joint Meeting of the Institution with the American Society of Mechanical Engineers in New York, which was cancelled owing to the outbreak of war.
openaire   +1 more source

Development of a Finite Element Approach to Mechanics, Transport and Biosynthesis in Tissue Engineering

2005
No ...
Sengers, B.G., Pullens, R.A.A., Oomens, C.W.J., Baaijens, F.P.T.   +3 more
openaire   +2 more sources

Assessing plant uptake and transport mechanisms of engineered nanomaterials from soil

MRS Bulletin, 2017
Abstract
Illya A. Medina-Velo, Jose R. Peralta-Videa, Jorge L. Gardea-Torresdey   +2 more
openaire   +1 more source

Engineering Scaffold Mechanical and Mass Transport Properties

2011
Biomaterial scaffolds must provide the 4Fs for regenerative medicine: Form, Fixation, Formation, and Function. Form is the ability to provide shape and volume matching within a given anatomic defect. Fixation is the ability to fix the scaffold to surrounding tissues.
openaire   +1 more source