Results 91 to 100 of about 2,759,873 (338)
AgricultureEnhancing the intelligence of Tiger nut harvesting equipment with the advancement of agricultural machinery is imperative. Mismatches between excavation feed rate and conveying-separating capacities hinder the efficiency of Tiger nut harvesters.
Sirui Chen +6 more
doaj +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection
Advanced Science, EarlyView.MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani +6 more
wiley +1 more source
Acta Polytechnica, 2013 The use of precast steel fibre reinforced concrete (SFRC) for tunnel segments is a relatively new application of this material. It was first applied in Italy in the 1980s. However, it did not begin to be widely applied until after 2000.
Jaroslav Beňo, Matouš Hilar
doaj
Prediction of subsidence due to underground mining by artificial neural networks [PDF]
, 2003 Alternatively to empirical prediction methods, methods based on influential functions and on mechanical model, artificial neural networks (ANNs) can be used for the surface subsidence prediction.
Ambrožič, Tomaž, Turk, Goran
core +1 more source
Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
Advanced Science, EarlyView.While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
A study of energy scavenging strategy in a tapping tree power [PDF]
, 2014 Energy harvesting has become one of the newest research attraction for both academic and industry fields. The energy is captured from external sources (thermal, wind, solar, vibration and hydrodynamic) and the energy source for energy harvesters is ...
Abdullah Alhamzi, Belal Mohammed
core
Slope stability in slightly fissured claystones and marls [PDF]
, 2015 The final publication is available at Springer via http://dx.doi.org/10.1007/s10346-014-0526-5The paper deals with the behavior of some characteristic soft rocks found in the Iberian Peninsula.
Alonso Pérez de Agreda, Eduardo +1 more
core +2 more sources
Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Advanced Science, EarlyView.Tumor‐derived extracellular vesicles program inflammatory lung premetastatic niches through selective delivery of long noncoding RNAs. This work reveals EVs‐associated lncOSLMT as a key driver of lung fibroblast activation via m6A‐dependent PTGS2 stabilization.
Hongbo Li +10 more
wiley +1 more source