Results 21 to 30 of about 4,424,668 (298)

Mapping the dynamics of force transduction at cell–cell junctions of epithelial clusters

eLife, 2014
Force transduction at cell-cell adhesions regulates tissue development, maintenance and adaptation. We developed computational and experimental approaches to quantify, with both sub-cellular and multi-cellular resolution, the dynamics of force ...
Mei Rosa Ng, Achim Besser, Joan S Brugge, Gaudenz Danuser   +3 more
doaj   +1 more source

Force-Induced Autophagy in Periodontal Ligament Stem Cells Modulates M1 Macrophage Polarization via AKT Signaling

Frontiers in Cell and Developmental Biology, 2021
Autophagy, a lysosomal degradation pathway, serves as a protective cellular mechanism in maintaining cell and tissue homeostasis under mechanical stimulation.
Nan Jiang, Danqing He, Yushi Ma, Junxiang Su, Xiaowen Wu, Shengjie Cui, Zixin Li, Yanheng Zhou, Huajie Yu, Yan Liu   +9 more
doaj   +1 more source

Mechanics: The forces of cancer [PDF]

Nature, 2012
The way cells physically interact with each other and their environment could help researchers understand the invasion and metastasis of solid tumours.
openaire   +2 more sources

Mechanically Optimize T Cells Activation by Spiky Nanomotors

Frontiers in Bioengineering and Biotechnology, 2022
T cell activation is vital for immune response initiation and modulation. Except for the strength of the interaction between T cell receptors (TCR) and peptides on major histocompatibility complex molecules (MHC), mechanical force, mediated by ...
Dongmei Fu, Dazhi Xie, Fei Wang, Bin Chen, Zhen Wang, Fei Peng   +5 more
doaj   +1 more source

Probing the Mechanisms of Translation with Force [PDF]

Chemical Reviews, 2014
Genetic information flows from DNA to RNA to protein. DNA is transcribed to yield messenger RNAs (the coding RNA), RNAs required for protein synthesis (ribosomal RNAs and transfer RNAs), and non-coding RNAs that often have regulatory functions (ncRNAs, including microRNAs, siRNAs, piRNAs,1 and others). Translation of messenger RNAs (mRNAs) produces the
Christian M, Kaiser, Ignacio, Tinoco
openaire   +2 more sources

Mechanical-Tunable Capillary-Force-Driven Self-Assembled Hierarchical Structures on Soft Substrate

, 2018
Capillary-force-driven self-assembly (CFSA) has been combined with many top-down fabrication methods to be alternatives to conventional single micro/nano manufacturing techniques for constructing complicated micro/nanostructures.
Deng Pan (47215), Hongwei Yuan (3038109), Jiawen Li (1454653), Dong Wu (140590), Zhaoxin Lao (1454647), Shengyun Ji (3986132), Jincheng Ni (4224664), Wulin Zhu (5844194), Yanlei Hu (1454659), Jiaru Chu (1454650)   +9 more
core   +3 more sources

Mechanical force determines chimeric antigen receptor microclustering and signaling [PDF]

Molecular Therapy
Yucai Wang, Xiangjun Chen, Wanli Liu
exaly   +2 more sources

Idealism as a Force: A Mechanical Analogy [PDF]

Monist, 1917
n ...
openaire   +1 more source

Force Mechanics

, 2023
This paper aims to outline some of the forces and the interactions that make up those forces, and the resulting “hyper-force” of superposition, using a mathematically linguistic equation.
openaire   +4 more sources

Mechanical Force Sensing in Tissues [PDF]

, 2014
Tissue size, shape, and organization reflect individual cell behaviors such as proliferation, shape change, and movement. Evidence suggests that mechanical signals operate in tandem with biochemical cues to properly coordinate cell behavior and pattern tissues.
Chanet, Soline, Martin, Adam
openaire   +3 more sources