Results 101 to 110 of about 1,797,968 (302)
Influence of stretch and pressure as mechanical stresses on skeletal muscle
Journal of Physical Fitness and Sports Medicine, 2013 Mechanical forces induced by skeletal muscle contraction generate intramuscular stresses as well as external tension. Skeletal muscle cells can sense and adapt to mechanical stresses to maintain cellular homeostasis.
Noriteru Morita +2 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
IEEE Access, 2019 Mechanoregulatory healing models, bioregulatory healing models, and mechanobioregulatory healing models have been developed to investigate the interaction among the mechanical environment, biological factors, and tissue differentiation during bone ...
Monan Wang, Ning Yang
doaj +1 more source
Glioma: the Mechanisms of Infiltrative Growth
Opera Medica et Physiologica, 2016 Malignant gliomas are primary brain tumors considered to be one of the deadliest cancers. Despite surgical intervention followed by aggressive radio- and chemo-therapies, average survival is approximately 15 months of diagnosis. Recurrent tumors resembling all the characteristics of the original tumor mass and growing in close vicinity to the original ...
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Elastic and Piezoresistive Properties of Nickel Carbides from First-Principles
, 2017 The nickel--carbon system has received increased attention over the past years due to the relevance of nickel as a catalyst for carbon nanotube and graphene growth, where Nickel carbide intermediates may be involved or carbide interface layers form in ...
Gemming, Sibylle +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
PLoS Computational Biology, 2019 Model simulations indicate that the response of growing cell populations on mechanical stress follows the same functional relationship and is predictable over different cell lines and growth conditions despite experimental response curves look largely ...
Paul Van Liedekerke +5 more
doaj +1 more source
Spatiotemporal establishment of dense bacterial colonies growing on hard agar. [PDF]
, 2019 The physical interactions of growing bacterial cells with each other and with their surroundings significantly affect the structure and dynamics of biofilms.
Cremer, Jonas +5 more
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