Results 71 to 80 of about 52,540 (262)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Mechanical Harvesting Feasible for White Asparagus

California Agriculture, 1965
Comparative yields for hand cutting and nonselective mechanical harvesting of white asparagus were determined during the 1964 cannery season, using an experimental harvester. In the tests, the machine-harvested all-white treatment on a peat soil produced
R Kepner
doaj  

Genetics of destemming in pepper: A step towards mechanical harvesting. [PDF]

Front Genet, 2023
Hill T, Cassibba V, Joukhadar I, Tonnessen B, Havlik C, Ortega F, Sripolcharoen S, Visser BJ, Stoffel K, Thammapichai P, Garcia-Llanos A, Chen S, Hulse-Kemp A, Walker S, Van Deynze A.   +14 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Once-over mechanical harvesting for cucumbers

California Agriculture, 1966
Cucumbers (for pickling) can soon be harvested with a commercial machine in a single once-over operation. A commercial prototype machine is available, and the feasibility of the once-over harvesting is enhanced by double-cropping possibilities in ...
M Zahara, W Sims
doaj  

Mechanical harvesting optimization and postharvest treatments to improve wine quality

OENO One, 2010
Aims: The aim of this work was to verify the influence of mechanical harvesting and postharvest treatments on wine composition. Methods and results: Trials were carried out in triplicate on cv. Montuni grapes. The estimated best setting frequency for the
Giuseppe Arfelli, Elisa Sartini, F. Bordini, Claudio Caprara, Fabio Pezzi   +4 more
doaj   +1 more source

Improvement of German Chamomile (Matricaria recutita L.) for Mechanical Harvesting, High Flower Yield and Essential Oil Content Using Physical and Chemical Mutagenesis. [PDF]

Plants (Basel), 2022
Ghareeb YE, Soliman SS, Ismail TA, Hassan MA, Abdelkader MA, Abdel Latef AAH, Al-Khayri JM, ALshamrani SM, Safhi FA, Awad MF, El-Moneim DA, Hassanin AA.   +11 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Increasing Permittivity and Mechanical Harvesting Response of PVDF-Based Flexible Composites by Using Ag Nanoparticles onto BaTiO₃ Nanofillers. [PDF]

Nanomaterials (Basel), 2022
Horchidan N, Ciomaga CE, Curecheriu LP, Stoian G, Botea M, Florea M, Maraloiu VA, Pintilie L, Tufescu FM, Tiron V, Rotaru A, Mitoseriu L.   +11 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source