Results 91 to 100 of about 273,808 (312)
Development of a friction model for the numerical simulation of clinching processes
FrictionIn numerical simulations of mechanical joining processes, such as clinching, modeling of material behavior is of decisive importance. In addition to the correct representation of plasticity and damage mechanisms, this primarily includes modeling of the ...
Max Böhnke +4 more
doaj +1 more source
Low-temperature solder for joining large cryogenic structures [PDF]
Three joining methods were considered for use in fabricating cooling coils for the National Transonic Facility. After analysis and preliminary testing, soldering was chosen as the cooling coil joining technique over mechanical force fit and brazing ...
Buckley, J. D., Sandefur, P. G., Jr.
core +1 more source
Electro-thermo-mechanical behaviours of laser joints for electric vehicle battery interconnects [PDF]
, 2019 An automotive battery pack used in electric vehicle (EV) comprises several hundred to a few thousand of individual Lithium-ion (Li-ion) cells when cylindrical cells are used to build the battery pack.
Barai, Anup +3 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Materials data handbook: Aluminum alloy 7075 [PDF]
A summary of the materials property information on aluminum alloy 7075 is presented. The scope of the information includes physical and mechanical properties of the alloy at cryogenic, ambient, and elevated temperatures.
Muraca, R. F., Whittick, J. S.
core +1 more source
3D modelling of Ti–6Al–4V linear friction welds [PDF]
, 2016 Linear friction welding (LFW) is a solid-state joining process that significantly reduces manufacturing costs when fabricating Ti–6Al–4V aircraft components.
Buhr, Clement +2 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Materials data handbook: Aluminum alloy 5456 [PDF]
A summary of the materials property information for aluminum alloy 5456 is presented. The scope of the information includes physical and mechanical property data at cryogenic, ambient, and elevated temperatures.
Muraca, R. F., Whittick, J. S.
core +1 more source
Process-oriented Flow Curve Determination at Mechanical Joining
Procedia Manufacturing, 2020 Abstract The accuracy of numerical simulation models for forming processes depends highly on the method for the flow curve determination. Numerous experimental tests exist to identify the flow curves of sheet metals, each with certain characteristics regarding stress states and achievable strains. In this paper stress state analysis are presented for
Jäckel, Mathias +10 more
openaire +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source