Results 111 to 120 of about 273,808 (312)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Mechanical characteristics of joints between glass fiber reinforced composite tubes and steel cylinder obtained by different fastening elements [PDF]
Scientific Technical Review, 2016 In this paper, investigation of tensile testing for specific assemblies of two elements, jointed by mechanical fasteners, are presented. One element is a specific small diameter tube.
Radulović Jovan, Čitaković Slobodan
doaj
Metals, 2019 In this paper, the fracture toughness of the thermo-mechanically affected zone (TMAZ) and the weld zone (WZ) of the TC17 titanium alloy linear friction welding joint was studied. The relationship between microstructure and fracture toughness of the joint,
Xiaohong Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Plasticity effects in subsequent simulations of car structures [PDF]
, 2003 In order to further reduce the weight of car components while at the same time\ud maintaining performance and safe life it is necessary to enhance the simulation process.
Kose, Kim, Rietman, Bert
core +1 more source
The Mechanism of Human Nonhomologous DNA End Joining [PDF]
Journal of Biological Chemistry, 2008 Double-strand breaks are common in all living cells, and there are two major pathways for their repair. In eukaryotes, homologous recombination is restricted to late S or G(2), whereas nonhomologous DNA end joining (NHEJ) can occur throughout the cell cycle and is the major pathway for the repair of double-strand breaks in multicellular eukaryotes ...
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Hybrid Joining of Dissimilar Thin Metallic Sheets—Mechanical Joining and Adhesive Bonding
CrystalsThis paper deals with joining dissimilar materials using thermal drilling technology as well as the combination of thermal drilling and adhesive bonding.
Anna Guzanová +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Mechanical and Tribological Behaviour of Surface-Graphitised Al-1100 Alloy
LubricantsThis study details the mechanical incorporation of graphite particles into the surface of aluminium (Al-1100) to fabricate surface composites using an electrical resistance heating-assisted pressing method. Initially, the aluminium surface is coated with
Baidehish Sahoo +2 more
doaj +1 more source