Results 131 to 140 of about 273,808 (312)

A comparison between single sided and double sided friction stir welded 8mm thick DH36 steel plate [PDF]

, 2012
As part of an ongoing process to fully evaluate the potential for friction stir welding (FSW) to be used in the shipbuilding industry, a comparison has been made between two variants of the process.
Cater, Stephen R., Galloway, Alexander, McPherson, Norman, Osman, M.M.   +3 more
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Investigations to improve the tool life during thermomechanical and incremental forming of steel auxiliary joining elements

Journal of Advanced Joining Processes
Modern vehicles as well as structures consist more and more often of a multi material mix. In addition to the use of light materials (e. g. aluminium) to optimise lightweight construction potential, higher strength alloys are being used more and more ...
T Borgert, AB Nordieker, E Wiens, W Homberg   +3 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Investigation of different process routes for joining thermoplastic composite/steel joints via the embedding of cold formed metallic pin structures

Journal of Advanced Joining Processes
This study focuses on the integration of continuous fiber-reinforced thermoplastics (CFRT) with metal components through the use of cold-formed pin structures.
Julian Popp, Dietmar Drummer
doaj   +1 more source

A comparison between single sided friction stir welded and submerged arc welded DH36 steel thin plate [PDF]

, 2012
The adoption of the friction stir welding (FSW) process into the shipbuilding industry is being considered as a medium term issue. Currently the data on friction stir welded mild steels tends to be fragmented, with critical areas being short on specific ...
Cater, Stephen R., Galloway, Alexander, McPherson, Norman, Wood, James   +3 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Dissimilar metal material joining by mechanical joining

Journal of Japan Institute of Light Metals, 2022
openaire   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source