Results 41 to 50 of about 32,954 (257)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 2022 S.51-60In the course of ongoing development of mechanical joining technologies, different technologies were developed in the last years, where often the necessary die as contrary die was substituted by a flat anvil. Using the example of dieless clinching,
Todtermuschke, M. +3 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
, 2022 Joining metals and ceramics plays a crucial role in many engineering applications. The current research aims to develop a simple and convenient approach for dissimilar material joining between SiC and Al alloys.
Du, Zehui +9 more
core +1 more source
A MECHANISM OF CHROMOSOMAL REARRANGEMENTS: THE ROLE OF HETEROCHROMATIN AND ECTOPIC JOINING [PDF]
Genetics, 1978 ABSTRACT Clusters of breaks at certain intercalary heterochromatin sites producing chromosomal rearrangements are reported in four endemic species (24 strains) of Hawaiian Drosophila. In laboratory strains of these species we observed some types of changes in chromosome structure that were predicted in our earlier studies (Yoon and ...
J S, Yoon, R H, Richardson
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Dissimilar joining between aluminium alloy (AA 6111) and thermoplastics using friction stir welding
, 2015 In this work, friction stir welding was used to produce shear overlap joints between aluminium and a thermoplastic (AA 6111 to polyphenylene sulphide). The process uses the friction stir welding tool to create metallic chips which merge with the molten ...
Melander, Arne,, Ratanathavorn, Wallop,
core +1 more source
Alternative end-joining mechanisms: a historical perspective [PDF]
Frontiers in Genetics, 2013 In the presence of functional DNA repair pathways, DNA double-strand breaks (DSBs) are mainly repaired by non-homologous end-joining (NHEJ) or homologous recombination (HR), two conserved pathways that protect cells from aberrant chromosomal rearrangements.
openaire +4 more sources
Mechanism of eIF6-mediated Inhibition of Ribosomal Subunit Joining [PDF]
Journal of Biological Chemistry, 2010 During the process of ribosomal assembly, the essential eukaryotic translation initiation factor 6 (eIF6) is known to act as a ribosomal anti-association factor. However, a molecular understanding of the anti-association activity of eIF6 is still missing.
Gartmann, M. +5 more
openaire +3 more sources