Results 121 to 130 of about 3,065,991 (332)
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
The Influence of Phosphorus and Sulphur on the Mechanical Properties of Steel [PDF]
H. C. H. CARPENTER
openalex +1 more source
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Probing the mechanical properties of graphene using a corrugated elastic substrate
The exceptional mechanical properties of graphene have made it attractive for nano-mechanical devices and functional composite materials. Two key aspects of graphene's mechanical behavior are its elastic and adhesive properties.
Cesar Chialvo+8 more
core +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
The Plasma Immersion Ion Implantation (PIII) nitriding was used to form a modified layer rich in expanded austenite (γN) and expanded ferrite (αN) phases in super duplex steel.
Bruna Corina Emanuely Schibicheski Kurelo+6 more
doaj +1 more source
Physicochemical Properties of the Surface of Aqueous Solutions. IV. Classification of Mechanical Behavior of Several Aqueous Surfaces [PDF]
Hideo Kimizuka
openalex +1 more source
In vivo assessment of the mechanical properties of the child cortical bone using quantitative computed tomography [PDF]
The mechanical properties of the rib cortical bone are extremely rare on children due to difficulties to obtain specimens to perform conventional tests. Some recent studies used cadaveric bones or bone tissues collected during surgery but are limited by ...
BERMOND, François+7 more
core +3 more sources
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source