Results 161 to 170 of about 995,645 (283)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Continuous Filament Fabrication Technology and Its Mechanical Properties for Thin-Walled Component. [PDF]

Materials (Basel)
Kozior T, Bochnia J, Hajnys J, Mesicek J.   +3 more
europepmc   +1 more source

Rock Mechanical Property Influenced by Inhomogeneity [PDF]

, 2012
Yunliang Tan, Dongmei Huang, Ze Zhang
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Protocol to quantify mechanical properties of cells using optical tweezers. [PDF]

STAR Protoc
Rodenburg WS, Eeftens JM.
europepmc   +1 more source

Development of polylactic acid‐untreated bamboo filler composite and its chemical and mechanical properties [PDF]

S. Sasaki, Kunitake Naito, Michimasa UCHIDATE   +2 more
openalex   +1 more source

Mechanical properties UHMWPE/alumina nanofibers nanocomposite

, 2020
А.A. Куулар, A. Voronin, I. A. Markevich, T. V. Bermeshev, М. М. Симунин   +4 more
openalex   +1 more source

Mechanical and Durability Properties of Fly Ash Based Concrete Exposed to Marine Environment [PDF]

, 2017
Sarfaraz Ahmed Kagadgar, Suman Saha, C. Rajasekaran   +2 more
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Key Factors Influencing the Mechanical Properties of Binodal Decomposed Metallic Glass Composites. [PDF]

Materials (Basel)
Wang Y, Zheng G, Li M.
europepmc   +1 more source