Results 171 to 180 of about 1,339,441 (314)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Polylactide microcapsules and films: preparation and properties

open access: yes, 2009
This thesis aims at preparation of hollow polylactide (PLA) microcapsules for use as ultrasound contrast agents with controlled size, structure and mechanical and thermal properties.
Sawalha, H.I.M.
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Electrical and mechanical properties of conductive elastic bands as wearable sensors. [PDF]

open access: yesSci Rep
Mustafa E   +4 more
europepmc   +1 more source

Synthesis, Microstructure and Mechanical Properties of Titanium with Controlled Levels of Porosity

open access: yes, 2014
Porous titanium (Ti) products have many applications due to their excellent corrosion resistance, high strength-to-weight ratio, high specific surface area, etc.
Xu, Qian
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Micro-mechanical predictive modelling as an aid to CAD based analysis of composite sporting equipment

open access: yes, 2008
The sport and leisure industry in New Zealand (NZ) has the potential to become a major user of composite materials. Given the size of NZ industry, design and manufacturing strategies based on virtual engineering should be developed to suit NZ ...
Ewart, Paul
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy